Heart function challenged with β-receptor agonism or antagonism in a heart failure model

Cardiovascular Drugs and Therapy

Volumn 15, Issue 6, 2001, Pages 479-486

  Washington, Benny ^a   Butler, Karyn ^b   Doye, Angelia A ^c   Jang, Monica ^d   Hajjar, Roger J ^d   Gwathmey, Judith K ^c  

^a TENNESSEE STATE UNIVERSITY   (United States)

^b MOREHOUSE SCHOOL OF MEDICINE   (United States)

^c BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

blocker; Heart failure; Isoproterenol turkey

Indexed keywords

BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; CARTEOLOL; IMMUNOGLOBULIN G; ISOPRENALINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC RECEPTOR BLOCKING; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DRUG MECHANISM; HEART DEVELOPMENT; HEART DILATATION; HEART FAILURE; HEART FUNCTION; HEART LEFT VENTRICLE FUNCTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART RATE; HEART VENTRICLE PRESSURE; IMMUNOGLOBULIN BLOOD LEVEL; LONG TERM EXPOSURE; NONHUMAN; PERINATAL DEVELOPMENT; PRIORITY JOURNAL; SURVIVAL; TACHYCARDIA; TURKEY (BIRD);

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; ANIMALS, NEWBORN; BLOOD PRESSURE; CARDIOMYOPATHY, DILATED; CARTEOLOL; CELL SIZE; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HEART; HEART FAILURE, CONGESTIVE; HEART RATE; IMMUNOGLOBULIN G; ISOPROTERENOL; MYOCARDIUM; RATS; TURKEYS; VENTRICULAR FUNCTION, LEFT;

EID: 0035713837     PISSN: 09203206     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013755402109     Document Type: Article

References (30)

1. Effect of long-term β-adrenergic receptor blockade in congestive cardiomyopathy
2. β1-and β2-adrenergic-receptor subpopulations in nonfailing and failing human ventricular myocardium: Coupling of both receptor subtypes to muscle contraction and selective β1-receptor down-regulation in heart failure
3. Role of intracellular calcium handling in force-interval relationships of human ventricular myocardium
4. Influence of the force-frequency relationship on hemodynamics and left ventricular function in patients with nonfailing hearts and in patients with dilated cardiomyopathy
5. Altered myocardial force-frequency relation in human heart failure
6. Myocardial force-frequency defect in mitral regurgitation heart failure is reversed by forskolin
7. Cellular and molecular remodeling in a heart failure model treated with the βblocker carteolol
8. Mechanisms of membrane-receptor regulation
9. Effects of bucindolol on neurohormonal activation in congestive heart failure
10. β-adrenergic blockade in congestive heart failure: Answering the old questions
11. Marcel. The cardiac adrenergic transmembrane signaling system in heart failure
12. 2+ ATPase and phosphorylation level of phospholamban
13. Contribution of abnormal sarcoplasmic reticulum. ATPase activity to systolic and diastolic dysfunction in human heart failure
14. Deficient production of cyclic AMP: Pharmacologic evidence of an important cause of contractile dysfunction in patients with end-stage heart failure
15. β-blocker treatment of dilated cardiomyopathy. Beneficial effect of cartelol in mice
16. Endothelium-dependent effects of carteolol
17. Pathophysiological and biochemical characterization of an avian model of dilated cardiomyopathy: Comparison to findings in human dilated cardiomyopathy
18. Decreased energy reserve in an animal model of dilated cardiomyopathy
19. Physiological effects of adenoviral gene transfer of sarcoplasmic reticulum calcium ATPase in isolated rat myocytes
20. Beta-adrenergic effect of antibodies from chagasic patients and normal lymphocytes on isolated rat atria
21. Autoantibodies against beta-adrenoceptors in human idiopathic dilated cardiomyopathy
22. A circulating IgG in Chagas' disease which binds to β-adrenoceptors of myocardium and modulated their activity
23. Etude immunologique dans les myocardiopathies dilatees
24. Short-term hemodynamic effects of immunoadsorption in dilated cardiomyopathy
25. The force-interval relationship in human myocardium
26. Different beta-adrenoceptor-effector coupling in human ventricular and atrial myocardium
27. Evidence against spare or uncoupled beta-adrenoceptors in the human heart
28. Effect of inotropic stimulation on the negative force-frequency relationship in the failing human heart
29. Long-term β-blockade in dilated cardiomyopathy: Effects of short- and long-term metoprolol treatment followed by withdrawal and readministration of metoprolol
30. Why do patients with congestive heart failure tolerate the initiation of β-blocker therapy?