Fed-batch cultivation for the production of clavulanic acid by an immobilized Streptomyces clavuligerus mutant

World Journal of Microbiology and Biotechnology

Volumn 17, Issue 9, 2001, Pages 869-872

  Kim, Il Chul ^a   Kim, Chang Ho ^b   Hong, Suk In ^a   Kim, Seung Wook ^c  

^a Korea University   (South Korea)

^b Bioscience and Biotechnology   (United Kingdom)

^c NONE

Author keywords

Clavulanic acid; Fed batch cultivation; Immobilization; Streptomyces clavuligerus KK

Indexed keywords

FUNGI; STREPTOMYCES CLAVULIGERUS;

EID: 0035708176     PISSN: 09593993     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1013895617923     Document Type: Article

References (12)

1. Clavulanic acid: Properties, Biosynthesis, and Fermentation
2. Naturally occurring β-lactamase inhibitors with antibacterial activity
3. Production of dextransucrase by Leeconostoc mesenteroides immobilized in calcium-alginate beads, batch and fed-batch fermentation
4. Genetic studies of antibiotics and other secondary metabolites
5. Production and characteristics of clavulanic acid
6. Effect of inorganic salts and various bioreactors on the production of clavulanic acid
7. Simultaneous production and decomposition of clavulanic acid during Streptomyces clavuligerus cultivation
8. Production of cellulase on mixtures of xylose and cellulose in a fed-batch process
9. Clavulanic acid: A beta-lactamase-inhibiting beta-lactam from Streptomyces clavuligerus
10. Evolution of Beta-lactamase inhibitors
11. Isolation and biochemical characterization of Streptomyces clavuligerus mutants in the biosynthesis of clavulanic acid and cephamycin C*
12. Optimization of fed-batch penicillin fermentation