Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: Gene structure, tissue expression, and localization of the protein to peroxisomes

Genomics

Volumn 79, Issue 2, 2002, Pages 162-168

  Björkman, Jonas ^a   Gould, Stephen J ^b   Crane, Denis I ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Gene structure; Mouse; Peroxisome; Peroxisome biogenesis; PEX13; SH3 protein

Indexed keywords

MEMBRANE PROTEIN; PROTEIN PEX13; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; DEGENERATIVE DISEASE; DISORDERS OF PEROXISOMAL FUNCTIONS; EXON; GENE DISRUPTION; GENE EXPRESSION; GENE LOCATION; GENE MUTATION; GENE STRUCTURE; LIVER; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PEROXISOME; PRIORITY JOURNAL; PROTEIN LOCALIZATION; SEQUENCE HOMOLOGY; SKIN FIBROBLAST; TESTIS;

ANIMALIA;

EID: 0035707925     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.2002.6697     Document Type: Article

References (30)

1. Peroxisomal disorders
2. Peroxisomal diseases
3. A unified nomenclature for peroxisome biogenesis factors
4. Import of proteins into peroxisomes
5. Peroxisome biogenesis disorders
6. Pex13p is an SH3 protein of the peroxisome membrane and a docking factor for the predominantly cytoplasmic PTS1 receptor
7. The SH3 domain of the Saccharomyces cerevisiae peroxisomal membrane protein Pex13p functions as a docking site for Pex5p, a mobile receptor for the import of PTS1-containing proteins
8. Identification of Pex13p a peroxisomal membrane receptor for the PTS1 recognition factor
9. Involvement of Pex13p in Pex14p localization and peroxisomal targeting signal 2-dependent protein import into peroxisomes
10. Pex14p, a peroxisomal membrane protein binding both receptors of the two PTS-dependent import pathways
11. Pex17p of Saccharomyces cerevisiae is a novel peroxin and component of the peroxisomal protein translocation machinery
12. Interaction of Pex5p, the type 1 peroxisome targeting signal receptor, with the peroxisomal membrane proteins Pex14p and Pex13p
13. PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders
14. Nonsense and temperature-sensitive mutations in PEX13 are the cause of complementation group H of peroxisome biogenesis disorders
15. Genomic structure of PEX13, a candidate peroxisome biogenesis disorder gene
16. Organisation and expression of eucaryotic split genes coding for proteins
17. Sequence and structure-based prediction of eukaryotic protein phosphorylation sites
18. Signal scan: A computer program that scans DNA sequences for eukaryotic transcription elements
19. The peroxisome biogenesis disorder group 4 gene, PXAAA1, encodes a cytoplasmic ATPase required for stability of the PTS1 receptor
20. PEX7 gene structure, alternative transcripts, and evidence for a founder haplotype for the frequent RCDP allele, L292ter
21. Defective peroxisome membrane synthesis due to mutations in human PEX3 causes ZeIlweger syndrome, complementation group G
22. A mouse model for Zellweger syndrome
23. Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder
24. Cre recombinase: The universal reagent for genome tailoring
25. New developments of a transcription factors database
26. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
27. The Pichia pastoris PAS4 gene encodes a ubiquitin-conjugating enzyme required for peroxisome assembly
28. A common PEX1 frameshift mutation in patients with disorders of peroxisome biogenesis correlates with the severe Zellweger syndrome phenotype
29. Purification of peroxisomes from livers of normal and clofibrate-treated mice
30. Localization of a portion of extranuclear ATM to peroxisomes