Comparative efficacy of BMS-284756, a new fluoroquinolone, versus established antimicrobial regimens for the treatment of experimental intra-abdominal sepsis in rats

Current Therapeutic Research - Clinical and Experimental

Volumn 62, Issue 12, 2001, Pages 862-868

  Cisneros, Ronald L ^a   Onderdonk, Andrew B ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

Antimicrobial; Fluoroquinolone; Intra abdominal infection

Indexed keywords

CLINDAMYCIN; GARENOXACIN; GENTAMICIN; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SULTAMICILLIN;

ABDOMINAL ABSCESS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOPSY; BODY SURFACE; BODY WEIGHT; CONTROLLED STUDY; DOSE CALCULATION; DRUG EFFICACY; INOCULATION; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS; TREATMENT OUTCOME;

EID: 0035699361     PISSN: 0011393X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0011-393X(01)80091-6     Document Type: Article

References (11)

1. Efficacy of ampicillin/sulbactam for the treatment of experimental intra-abdominal sepsis
2. Efficacy of a combination of ciprofloxacin and clindamycin for the treatment of experimental intraabdominal sepsis
3. Therapeutic efficacy of 29 antimicrobial regimens in experimental intraabdominal sepsis
4. Experimental intra-abdominal abscesses in rats: Development of an experimental model
5. Antimicrobial therapy of experimental intraabdominal sepsis
6. Antibacterial spectrum of a novel desfluoro (6) quinolone, BMS-284756
7. Mechanism of fluoroquinolone action
8. Rapid microbiological assay for chloramphenicol and tetracyclines
9. Antimicrobial resistance of Streptococcus pneumoniae recovered from outpatients in the United States during the winter months of 1994 to 1995: Results of a 30-center national surveillance study