A pharmacokinetic study of amoxycillin in febrile beagle dogs following repeated administrations of endotoxin

Journal of Veterinary Pharmacology and Therapeutics

Volumn 24, Issue 6, 2001, Pages 379-383

  Vachon, P ^a   Masse R ^a   Moreau, J P ^a   Fortin, D ^a   Beaudry, F ^a  

^a MDS Inc   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ENDOTOXIN;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG SCREENING; FEVER; LIQUID CHROMATOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RECTUM TEMPERATURE; SEPTIC SHOCK; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; AMOXICILLIN; ANIMALS; AREA UNDER CURVE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DOG DISEASES; DOGS; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEVER; LIPOPOLYSACCHARIDES; MALE; PENICILLINS;

ANIMALIA; CANIS FAMILIARIS; ESCHERICHIA COLI;

EID: 0035698268     PISSN: 01407783     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2885.2001.00359.x     Document Type: Article

References (16)

1. Pharmacokinetics and tissue distribution of amoxicillin in healthy and Salmonella Typhimuriuminoculated pigs
2. Iron absorption and pyrexia
3. A quantitative study of gastric secretion associated with pyrexia
4. Amoxycillin: Clinical trials in dogs and cats
5. The influence of endotoxin-induced pyrexia on the pharmacokinetics of gentamicin in the rabbit
6. Differential effect of impaired renal function on the kinetics of clavulanic acid and amoxicillin
7. Bioavailability of amoxicillin, ampicillin and hetacillin in the dog
8. Bioavailability of different forms of am-oxycillin administered orally to dogs
9. Changes of pharmacokinetics of trimetoprim after pretreatment with streptococcal peptidoglycan
10. Plasma profiles of IL-6 and TNF with fever-inducing doses of lipopolysaccharide in dogs
11. Streptococcus pneumoniae pneumonia in mice: Optimal amoxicillin dosing predicted from pharmacokinetic-pharmacodynamic model
12. The pharmacologic consequences of fever
13. The influence of pyrogen induced fever on the absorption of sulfa drugs
14. Effect of feeding on plasma antibiotic concentrations in Greyhounds given ampicillin and amoxycillin by mouth