Induction of intestinal rotavirus-specific antibodies in respiratory, but not gut, lymphoid tissues following mucosal immunization of mice with inactivated rotavirus

Virology

Volumn 291, Issue 2, 2001, Pages 235-240

  Coffin, Susan E ^a,b   Clark, Stephanie L ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

IgA; Inactivated virus; Mouse; Protection; Respiratory tract; Rotavirus; Vaccine

Indexed keywords

IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INACTIVATED VIRUS VACCINE; VIRUS ANTIBODY;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ARTICLE; CONTROLLED STUDY; FEMALE; IMMUNIZATION; INTESTINE LYMPHATIC TISSUE; INTESTINE MUCOSA; MOUSE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT MUCOSA; ROTAVIRUS; VIRUS INFECTION;

RHESUS ROTAVIRUS; ROTAVIRUS;

EID: 0035697366     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1180     Document Type: Article

References (21)

1. Characterization of mouse nasal lymphocytes isolated by enzymatic extraction with collagenase
2. Oral immunization with recombinant Norwalk virus-like particles induces a systemic and mucosal immune response in mice
3. Respiratory tract defenses: Role of mucosal lymphoid tissues
4. Antibody-independent protection against rotavirus infection of mice stimulated by intranasal immunization with chimeric VP4 or VP6 protein
5. Migration of antigen-presenting cell B cells from periphery of mucosal lymphoid tissues may induce intestinal antigen-specific IgA following parenteral immunization
6. Induction of virus-specific antibody production by lamina propria lymphocytes following intramuscular inoculation with rotavirus
7. Immunologic correlates of protection against rotavirus challenge after intramuscular immunization of mice
8. Psoralen preparation of antigenically intact noninfectious rotavirus particles
9. Rotavirus-specific intestinal immune response in mice assessed by enzyme-linked immunospot assay and intestinal fragment culture
10. Oral inoculation of mice with low doses of microencapsulated, noninfectious rotavirus induces virus-specific antibodies in gut-associated lymphoid tissue
11. Use of Peyer's patch and lymph node cultures to compare local immune response to Morganella morganii
12. Antibody-dependent and -independent protection following intranasal immunization of mice with rotavirus particles
13. Effectiveness of intranasal immunization with HIV-gp160 and an HIV-1 Env CTL epitope peptide (E7) in combination with the mucosal adjuvant LT(R192G)
14. Normal induction of oral tolerance in the absence of a functional IL-12-dependent IFN-gamma signaling pathway
15. Response of mice to rotaviruses of bovine or primate origin as assessed by radioimmunoassay, radioimmunoprecipitation, and plaque reduction neutralization
16. Rotavirus 2/6 viruslike particles administered intranasally with cholera toxin, Escherichia coli heat-labile toxin (LT), and LT-R192G induce protection from rotavirus challenge
17. Rotavirus virus-like particles administered mucosally induce protective immunity
18. Expression of the mucosal homing receptor alpha4beta7 correlates with the ability of CD8+ memory T cells to clear rotavirus infection
19. Serum and intestinal isotype antibody response and correlates of protective immunity to human rotavirus in a gnotobiotic pig model of disease
20. Development of an adult mouse model for studies on protection against rotavirus
21. The memory B cell subset responsible for the secretory IgA response and protective humoral immunity to rotavirus expresses the intestinal homing receptor, alpha4beta7