Poliovirus 3C protease-mediated degradation of transcriptional activator p53 requires a cellular activity

Virology

Volumn 291, Issue 2, 2001, Pages 260-271

  Weidman, Mary K ^a   Yalamanchili, Padmaja ^a   Ng, Bryant ^a   Tsai, Weimin ^a   Dasgupta, Asim ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLULOSE PHOSPHATE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; OCTAMER BINDING FACTOR; PROTEIN P53; PROTEINASE; TATA BINDING PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; VIRUS ENZYME;

ARTICLE; CONTROLLED STUDY; HELA CELL; HUMAN; HUMAN CELL; METABOLIC INHIBITION; NONHUMAN; POLIOMYELITIS VIRUS; PRIORITY JOURNAL; PROTEIN DEGRADATION; RNA SYNTHESIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; VIRUS CELL INTERACTION;

POLIOVIRUS; VACCINIA VIRUS;

EID: 0035695178     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1215     Document Type: Article

References (48)

1. Two types of death of poliovirus-infected cells: Caspase involvement in the apoptosis but not cytopathic effect
2. Pro kills cells by apoptosis
3. Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53
4. A cellular cofactor facilitates efficient 3CD cleavage of the poliovirus P1 precursor
5. Crystal structure of p53 tumor suppressor DNA complex: Understanding tumorigenic mutation
6. Degradation of nuclear oncoproteins by the ubiquitin proteolysis system in vitro
7. A transcriptionally active form of TFIIIC is modified in poliovirus-infected HeLa cells
8. Poliovirus proteinase 3C converts an active form of transcription factor IIIC to an inactive form: A mechanism for inhibition of host cell polymerase III transcription by poliovirus
9. Direct cleavage of human TATA-binding protein by poliovirus protease 3C in vivo and in vitro
10. Inhibition of transcription factor activity by poliovirus
11. Purification of host factor required for in vitro transcription of poliovirus RNA
12. Site-directed mutagenesis of proteinase 3C results in a poliovirus deficient in synthesis of viral RNA polymerase
13. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
14. Cap-independent translation of mRNA conferred by encephalomyocarditis virus 5′ sequence improves the performance of the vaccinia virus/bacteriophage T7 hybrid expression system
15. Association of cap binding protein with eukaryotic initiation factor 3 in initiation factor preparations from uninfected and poliovirus infected HeLa cells
16. Wild-type p53 activates transcription in vitro
17. Ubiquitination
18. The elF 4G-elF 4E complex is the target for direct cleavage by the rhinovirus 2A proteinase
19. Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants
20. Site directed mutagenesis of the putative catalytic triad of poliovirus 3C proteinase
21. Crystal structure of the tetramerization domain of the p53 tumor suppressor at 1.7 angstroms
22. Inhibition of cell functions by RNA-virus infections
23. Identification of p53 as a sequence-specific DNA binding protein
24. An RNA polymerase II transcription factor inactivated in poliovirus-infected cells copurifies with transcription factor TFIID
25. Loss of a phosphorylated form of transcription factor CREB/ATF in poliovirus-infected cells
26. Viral proteinases
27. Picornavirus protein processing - Enzymes, substrates, and genetic regulation
28. Reversal of in vitro p53 squelching by both TFIIB and TFIID
29. The p53 activation domain binds the TATA box-binding polypeptide in holo-TFIID, and a neighboring p53 domain inhibits transcription
30. Cleavage of cap binding protein complex polypeptide p220 is not affected by second poliovirus protease 2A
31. Association of heat shock protein 70 with enterovirus capsid precursor P1 in infected human cells
32. Identification of a cyclic-AMP-responsive element within the rat somatostain gene
33. Poliovirus proteinase 3C: Large-scale expression, purification, and specific cleavage acidity on natural and synthetic substrates in vitro
34. Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of interleukin-1 beta converting enzyme
35. Inhibition of rRNA synthesis by poliovirus: Specific inactivation of transcription factor
36. Infection of HeLa cells with poliovirus results in modification of a complex that binds to rRNA promoter
37. The E6 oncoprotein encoded by human papillomavirus type 16 and 18 promotes the degradation of p53
38. DNA binding domain and subunit interactions of transcription factor IIIC revealed by dissection with poliovirus 3C protease
39. 2A proteinase of coxsackie and rhinovirus cleave peptides derived from elF-4 gamma via a common recognition motif
40. Regulation of apoptosis by viral gene products
41. Apoptosis-inducing and apoptosis-preventing functions of poliovirus
42. p53 transcriptional activation mediated by coactivators TAFII40 and TAFII60
43. p53 function and dysfunction
44. pro cleaves the TATA-binding protein but does not inhibit host cell RNA polymerase II transcription in vitro
45. pro
46. pro) inhibits formation of TBP-TATA box complex in vitro
47. Pro
48. Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53