Analysis of the phosphorylation status of Epstein-Barr virus LMP2A in epithelial cells

Virology

Volumn 291, Issue 2, 2001, Pages 208-214

  Scholle, Frank ^a,b   Longnecker, Richard ^b   Raab Traub, Nancy ^a,b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN LMP2A; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ARTICLE; CONTROLLED STUDY; EPITHELIUM CELL; EPSTEIN BARR VIRUS; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; VIRUS MUTATION; VIRUS REACTIVATION;

HUMAN HERPESVIRUS 4;

EID: 0035694857     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.2001.1197     Document Type: Article

References (25)

1. Epstein-Barr virus latent gene transcription in nasopharyngeal carcinoma cells: Coexpression of EBNA1, LMP1, and LMP2 transcripts
2. An Epstein-Barr virus transformation-associated membrane protein interacts with src family tyrosine kinases
3. Consistent transcription of the Epstein-Barr virus LMP2 gene in nasopharyngeal carcinoma
4. Epstein-Barr virus LMP2A drives B cell development and survival in the absence of normal B cell receptor signals
5. Requirement of the SH3 and SH2 domains for the inhibitory function of tyrosine protein kinase p50csk in T lymphocytes
6. Signaling-induced association of a tyrosine-phosphorylated 36-kDa protein with p50csk
7. Identification of latent membrane protein 2A (LMP2A) domains essential for the LMP2A dominant-negative effect on B-lymphocyte surface immunoglobulin signal transduction
8. The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transduction
9. Tyrosine 112 of latent membrane protein 2a is essential for protein tyrosine kinase loading and regulation of Epstein-Barr virus latency
10. Csk suppression of Src involves movement of Csk to sites of Src activity
11. Epstein-Barr virus and its replication
12. An Epstein-Barr virus protein associated with cell growth transformation interacts with a tyrosine kinase
13. A second Epstein-Barr virus membrane protein (LMP2) is expressed in latent infection and colocalizes with LMP1
14. Signal transduction by the alpha 6 beta 4 integrin: Distinct beta 4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes
15. Integral membrane protein 2 of Epstein-Barr virus regulates reactivation from latency through dominant negative effects on protein-tyrosine kinases
16. Epstein-Barr virus protein LMP2A regulates reactivation from latency by negatively regulating tyrosine kinases involved in slg-mediated signal transduction
17. An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinking
18. Epstein-Barr virus latent membrane protein 2A blocks calcium mobilization in B lymphocytes
19. Antigen receptor tail clue
20. Epithelial cell adhesion to extracellular matrix proteins induces tyrosine
21. Epstein-Barr virus LMP2A transforms epithelial cells, inhibits cell differentiation, and activates Akt
22. SH2 domains recognize specific phosphopeptide sequences
23. Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src
24. Latent membrane protein 2A-mediated effects on the phosphatidyl inositol 3-kinase/akt pathway
25. Signal transduction by lymphocyte antigen receptors