Comparison of ondansetron-dexamethasone-lorazepam versus metoclopramide-dexamethasone-lorazepam in the control of cisplatin induced emesis

Journal of the Medical Association of Thailand

Volumn 84, Issue 7, 2001, Pages 966-972

  Manusirivithaya, Sumonmal ^a   Isariyodom, Pawares ^b   Chareoniam, Viruch ^b   Sungsab, Danai ^b  

^a NAVAMINDRADHIRAJ UNIVERSITY   (Thailand)

^b Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

Cisplatin; Emesis; Metoclopramide; Ondansetron

Indexed keywords

CISPLATIN; CYCLOPHOSPHAMIDE; DEXAMETHASONE; LORAZEPAM; METOCLOPRAMIDE; ONDANSETRON;

ADULT; AGED; ANTIEMETIC ACTIVITY; ARTICLE; CHEMOTHERAPY INDUCED EMESIS; CLINICAL ARTICLE; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONSTIPATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIARRHEA; DRUG EFFECT; DRUG EFFICACY; DRUG INDUCED DISEASE; DRUG INFUSION; DRUG RESPONSE; DYSTONIA; FEMALE; HEADACHE; HUMAN; MALE; NAUSEA; OVARY CANCER; PARAMETER; RANDOMIZATION; RANDOMIZED CONTROLLED TRIAL; SEDATION;

ADULT; AGED; ANTIEMETICS; ANTINEOPLASTIC AGENTS; CHI-SQUARE DISTRIBUTION; CISPLATIN; DEXAMETHASONE; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; LORAZEPAM; METOCLOPRAMIDE; MIDDLE AGED; ONDANSETRON; OVARIAN NEOPLASMS; TREATMENT OUTCOME; VOMITING;

EID: 0035686269     PISSN: 01252208     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Gralla RJ, Itri LM, Pisko SE, et al. Anti-emetic efficacy of high dose metoclopramide : Randomized trial with placebo and prochlorperazine in patients with chemotherapy-induced nausea and vomiting. N Engl J Med 1981; 305: 905-9.
2. Kris MG, Gralla RJ, Clark RA, et al. Antiemetic control and prevention of side effects of anti-cancer therapy with lorazepam or diphenhydramine when used in combination with metoclopramide plus dexamethasone. Cancer 1987; 60: 2816-22.
3. Bateman DN, Rawlins MD, Simpson JM. Extrapyramidal reactions with metoclopramide. Br Med J 1985; 291: 930-2.
4. 3 receptor antagonist. Lancet 1987; 1: 1461-3.
5. Cubeddu LX, Hoffmann IS, Fuenmayor NT, Finn AL. Efficacy of ondansetron (GR38032F) and the role of serotonin in cisplatin-induced nausea and vomiting. N Engl J Med 1990; 322: 810-6.
6. Khojasteh A, Sartiano G, Tapazoglou E, et al. Ondansetron for the prevention of emesis induced by high-dose cisplatin. Cancer 1990; 66: 1101-5.
7. Joss RA, Bacchi M, Buser K, et al. Ondansetron plus dexamethasone is superior to ondansetron alone in the prevention of emesis in chemotherapynaive and previously treated patients. Swiss group for clinical cancer research. Ann Oncol 1994; 5: 253-8.
8. Roila F, Tonato M, Cognetti F. Prevention of cisplatin-induced emesis : a double blind multicenter randomized cross-over study comparing ondansetron and ondansetron plus dexamethasone. J Clin Oncol 1991; 9: 675-8.
9. Ahn MJ, Lee JS, Lee KH, Suh C, Choi SS, Kim SH. A randomized double-blind trial of ondansetron alone versus in combination with dexamethasone versus in combination with dexamethasone and lorazepam in the prevention of emesis due to cisplatin-based chemotherapy. Am J Clin Oncol 1994; 17: 150-6.
10. Demulder PHM, Seymaeve C, Vermorken JD, et al. Ondansetron compared with high-dose metoclopramide in prophylaxis of acute and delayed cisplatin-induced nausea and vomiting. Ann Intern Med 1990; 113: 834-40.
11. Marty M, Pouillart P, Scholl S, et al. Comparison of the 5-hydroxytryptamine-serotonin antagonist, ondansetron with high-dose metoclopramide in the control of cisplatin-induced emesis. N Engl J Med 1990; 322: 816-21.
12. Hainsworth J, Harvey W, Pendergrass K, et al. A single blind comparison of intravenous ondansetron with intravenous metoclopramide in the prevention of nausea and vomiting associated with high-dose cisplatin chemotherapy. J Clin Oncol 1991; 9: 721-8.
13. Tsavaris N, Charalambidis G, Ganas N, et al. Ondansetron versus metoclopramide as antiemetic treatment during cisplatin-based chemotherapy. A prospective study with special regard to electrolyte imbalance. Acta Oncol 1995; 34: 243-6.
14. Italian group for antiemetic research. Ondansetron + dexamethasone vs metoclopramide + dexamethasone + diphenhydramine in prevention of cisplatin-induced emesis. Lancet 1992; 340: 96-9.
15. The Italian group for antiemetic research. Difference in persistence of efficacy of two antiemetic regimens on acute emesis during cisplatin chemo-therapy. J Clin Oncol 1993; 11: 2396-404.
16. Navari RM, Province WS, Perrine GM, Kilgore JR. Comparison of intermittent ondansetron versus continuous infusion metoclopramide used with standard combination antiemetics in control of acute nausea induced by cisplatin chemotherapy. Cancer 1992; 72: 583-6.
17. Fanning J, Hilgers RD. Ondansetron and metoclopramide fail to prevent vomiting secondary to ultra-high-dose cisplatin- carboplatin chemotherapy. Obstet Gynecol 1994; 83: 601-4.
18. th ed. Philadelphia, Lippincott-Raven, 1997: 2707-9.
19. Kris MG, Gralla RJ, Tyson LB, et al. Improved control of cisplatin - induced emesis with high - dose metoclopramide and with combinations of metoclopramide, dexamethasone, and diphenhydramine, results of conservative trials in 255 patients. Cancer 1985; 55: 527-34.
20. Allan SG, Corbleet MA, Warrington PS, Golland IM, Leonard RCF, Smyth JF. Dexamethasone and high dose metoclopramide : efficacy in controlling cisplatin induced nausea and vomiting. BMJ 1984; 289: 878-9.
21. Stephens SH, Silvey VL, Wheeler RH. A randomized, double blind comparison of the antiemetic effect of metoclopramide and lorazepam with or without dexamethasone in patients receiving high dose cisplatin. Cancer 1990; 66: 443-6.
22. Gordon CJ, Pardur R, Zicarelli A, Cummings G, Al-Sarraf M. Metoclopramide versus metoclopramide and lorazepam. Superiority of combined therapy in the control of cisplatin-induced emesis. Cancer 1989; 63: 578-82.