T cell-mediated immune response enhances the severity of myocarditis in secondary cardiotropic virus infection in mice

Basic Research in Cardiology

Volumn 96, Issue 5, 2001, Pages 439-445

  Kishimoto, Chiharu ^a   Hiraoka, Yuji ^a   Takada, Hitoshi ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Coxsackie virus B3; Nude mice; Secondary infection; T cells

Indexed keywords

EPITOPE; GAMMA INTERFERON; INTERLEUKIN 6;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CONTROLLED STUDY; COXSACKIE VIRUS B3; DISEASE EXACERBATION; DISEASE SEVERITY; ENCEPHALOMYOCARDITIS VIRUS; ENTEROVIRUS; HEART MUSCLE INJURY; IMMUNE RESPONSE; INFLUENZA VIRUS A; INOCULATION; LYMPHOCYTE FUNCTION; LYMPHOCYTOPENIA; MALE; MOUSE; MYOCARDITIS; NONHUMAN; NUDE MOUSE; PICORNAVIRUS INFECTION; PROTEIN BLOOD LEVEL; REINFECTION; T LYMPHOCYTE;

ANIMALS; COXSACKIEVIRUS INFECTIONS; ENTEROVIRUS B, HUMAN; INTERFERON TYPE II; INTERLEUKIN-6; MALE; MICE; MICE, INBRED BALB C; MICE, NUDE; MYOCARDITIS; MYOCARDIUM; NECROSIS; T-LYMPHOCYTES;

EID: 0035686188     PISSN: 03008428     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003950170025     Document Type: Article

References (22)

1. Cytokine and murine Coxsackie virus B3 myocarditis. Interleukin-2 suppressed myocarditis in the acute stage but enhanced the condition in the subsequent stage
2. In vivo significance of T cells in the development of Coxsackie virus B3 myocarditis in mice. Immature but antigen-specific T cells aggravate cardiac injury
3. Analysis of the pathogenesis of Coxsackie virus B3 myocarditis. Comparison of myocarditic and amyocarditic Coxsackie virus B3 strains
4. Immunosuppression with high doses of cyclophosphamide reduces the severity of myocarditis, but increases the mortality in murine Coxsackie virus B3 myocarditis
5. A prospective case-control study of antibodies to Coxsackie B virus in idiopathic dilated cardiomyopathy
6. Immunologic behavior of lymphocytes in experimental viral myocarditis. Significance of T lymphocytes in the severity of myocarditis and silent myocarditis in BALB/c-nu/nu mice
7. + (immature T) subsets in the development of myocarditis
8. Antibody-mediated growth of influenza A NWS virus in macrophagelike cell line P388D1
9. Experimental influenza A virus myocarditis in mice. Light and electron microscopic, virologic, and hemodynamic study
10. Augmentation of murine lymphokineactivated killer (LAK) cell cytotoxicity by -cyclodextrin-benzaldehyde (CDBA)
11. Murine cell-mediated immune response recognizes an enterovirus group-specific antigen(s)
12. Secondary entero-virus infection in the murine model of myocarditis. Pathologic and immunologic aspects
13. Properties of Coxsackie virus B3 variants which are amyocarditic or myocarditic for mice
14. Interferon-γ and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells
15. Expression of myosin-class II major histocompatibility complexes in the normal myocardium occurs before induction of autoimmune myocarditis
16. Modification of viral myocarditis in mice by interleukin-6
17. Augmentation of pathogenesis of Coxsackie virus B3 infections in mice by exogenous administration of interleukin-1 and interleukin-2
18. Secondary heterotypic versus homotypic infection by Coxsackie B group viruses. Impact on early and late histopathological lesions and virus prominence
19. The murine CAR homolog is a receptor for Coxsackie B viruses and adenoviruses
20. Isolation of a common receptor for Coxsackie B viruses and adenoviruses 2 and 5
21. HCAR and MCAR: The human and mouse cellular receptors for subgroup C adenoviruses and group B Coxsackie viruses
22. Expression of Coxsackie virus and adenovirus receptor in hearts of rats with experimental autoimmune myocarditis