Interaction of MutS and Vsr: Some dominant-negative mutS mutations that disable methyladenine-directed mismatch repair are active in very-short-patch repair

Journal of Bacteriology

Volumn 183, Issue 21, 2001, Pages 6487-6490

  Lieb, Margaret ^a   Rehmat, Shehnaz ^a   Bhagwat, Ashok S ^a  

^a WAYNE STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 METHYLCYTOSINE; GENE PRODUCT; PROTEIN MUTS; PROTEIN VSR; UNCLASSIFIED DRUG;

ALLELISM; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONTROLLED STUDY; DEAMINATION; ESCHERICHIA COLI; GENE MUTATION; GENE TRANSLOCATION; MISMATCH REPAIR; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION;

ADENINE; ADENOSINE TRIPHOSPHATASES; ALLELES; BACTERIAL PROTEINS; BASE PAIR MISMATCH; DNA METHYLATION; DNA REPAIR; DNA, BACTERIAL; DNA-BINDING PROTEINS; ENDODEOXYRIBONUCLEASES; ESCHERICHIA COLI PROTEINS; MODELS, MOLECULAR; MUTATION; MUTS DNA MISMATCH-BINDING PROTEIN;

ESCHERICHIA COLI; NEGIBACTERIA;

EID: 0035685206     PISSN: 00219193     EISSN: None     Source Type: Journal    
DOI: 10.1128/JB.183.21.6487-6490.2001     Document Type: Article

References (24)

1. MutS mediates heteroduplex loop formation by a translocation mechanism
2. Initiation of methyl-directed mismatch repair
3. Overexpression of vsr in Escherichia coli is mutagenic
4. The Escherichia coli MutL protein stimulates binding of Vsr and MutS to heteroduplex DNA
5. The human mismatch recognition complex hMSH2-hMSH6 functions as a novel molecular switch
6. hMSH2-hMSH6 forms a hydrolysis-independent sliding clamp on mismatched DNA
7. The Escherichia coli MutL protein physically interacts with MutH and stimulates the MutH-associated endonuclease activity
8. Mismatch repair of deaminated 5-methyl-cytosine
9. Composite active site of an ABC ATPase: MutS uses ATP to verify mismatch recognition and authorize DNA repair
10. The crystal structure of DNA mismatch repair protein MutS binding to a G · T mismatch
11. Bacterial genes mutL, mutS, and dcm participate in repair of mismatches at 5-methylcytosine sites
12. Specific mismatch correction in bacteriophage lambda crosses by very short patch repair
13. Spontaneous mutation at a 5-methylcytosine hotspot is prevented by very short patch (VSP) mismatch repair
14. VSP repair: Reducing the cost of cytosine methylation
15. Very short patch repair of T:G mismatches in vivo: Importance of context and accessory proteins
16. The Vsr endonuclease of Escherichia coli: An efficient DNA repair enzyme and a potent mutagen
17. Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA
18. Dam-directed DNA mismatch repair
19. A gene required for very short patch repair in Escherichia coli is adjacent to the DNA cytosine methylase gene
20. Mispair specificity of methyl-directed DNA mismatch correction in vitro
21. Escherichia coli mutS-encoded protein binds to mismatched DNA base pairs
22. Recognition of a TG mismatch: The crystal structure of very short patch repair endonuclease in complex with a DNA duplex
23. Deletion mutation analysis of the mutS gene in Escherichia coli
24. Dominant negative mutator mutations in the mutS gene of Escherichia coli