Rheumatoid arthritis as an autoimmune disease caused by Proteus urinary tract infections: A proposal for a therapeutic protocol

Israel Medical Association Journal

Volumn 3, Issue 9, 2001, Pages 675-680

  Rashid, T ^a   Tiwana, H ^a   Wilson, C ^a   Ebringer, A ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Antimicrobial therapy; Proteus urinary tract infection; Rheumatoid arthritis

Indexed keywords

AMINO ACID; AMINOGLYCOSIDE ANTIBIOTIC AGENT; AMOXICILLIN; AMPICILLIN; ANTIBIOTIC AGENT; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; ANTIRHEUMATIC AGENT; CIPROFLOXACIN; COTRIMOXAZOLE; CYTOTOXIC AGENT; GENTAMICIN; GOLD SALT; HEMOLYSIN; HLA D ANTIGEN; IMMUNOSUPPRESSIVE AGENT; METHENAMINE; METHOTREXATE; METRONIDAZOLE; MINOCYCLINE; NETILMICIN; NONSTEROID ANTIINFLAMMATORY AGENT; NORFLOXACIN; PENICILLAMINE; RIFAMPICIN; SALAZOSULFAPYRIDINE; STEROID; TOBRAMYCIN; TRIMETHOPRIM; UNINDEXED DRUG;

ALLELE; AMINO ACID ANALYSIS; AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ANTIBODY DETECTION; ANTIBODY TITER; ANTIMICROBIAL THERAPY; AUTOIMMUNE DISEASE; BACTERIUM ISOLATION; CLINICAL PROTOCOL; CLINICAL TRIAL; DIET THERAPY; DISEASE COURSE; DRUG EFFECT; EARLY DIAGNOSIS; ENTEROBACTERIACEAE; ENVIRONMENTAL FACTOR; EPITOPE MAPPING; FLUID INTAKE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC MARKER; GENETIC SUSCEPTIBILITY; GRAM NEGATIVE INFECTION; HUMAN; META ANALYSIS; PALLIATIVE THERAPY; POPULATION GENETICS; POPULATION RISK; PROTEIN STRUCTURE; PROTEUS; PROTEUS MIRABILIS; REVIEW; RHEUMATOID ARTHRITIS; SEX DIFFERENCE; SIDE EFFECT; TREATMENT OUTCOME; TREATMENT PLANNING; URINARY TRACT INFECTION; URINE ACIDIFICATION;

ANTI-BACTERIAL AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIBODIES, BACTERIAL; ARTHRITIS, RHEUMATOID; FEMALE; HUMANS; MALE; MOLECULAR MIMICRY; PROTEUS INFECTIONS; PROTEUS MIRABILIS;

EID: 0035678422     PISSN: 15651088     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (40)

1. Epidemiology of rheumatic diseases: Rheumatoid arthritis
2. Sex ratio and hormones in HLA related rheumatic diseases
3. Association of the B-cell alloantigen DRw4 in rheumatoid arthritis
4. Putative amino acid sequence of HLA-DRβ chain contributing to rheumatoid arthritis susceptibility
5. The shared epitope hypothesis: An approach to understanding the molecular genetics of susceptibility to rheumatoid arthritis
6. Genes and arthritis
7. The influence of HLA-DRβ1 genes on disease severity in rheumatoid arthritis
8. Twin concordance rates for rheumatoid arthritis: Results from a nation-wide study
9. Antibodies to Proteus in rheumatoid arthritis
10. The susceptibility to rheumatoid arthritis maps to a T cell epitope shared by the HLA-Dw4 beta-1 chain and Epstein-Barr virus glycoprotein gp110
11. Klebsiella antibodies in ankylosing spondylitis and Proteus antibodies in rheumatoid arthritis
12. Anti-Proteus antibodies in rheumatoid arthritis same-sexed sibships
13. Elevation in anti-Proteus antibodies in patients with rheumatoid arthritis from Bermuda and England
14. Antibodies to four gram-negative bacteria in rheumatoid arthritis which share sequences with the rheumatoid arthritis susceptibility motif
15. Suppurative monoarthritis due to Proteus mirabilis with positive synovial Weil-Felix reaction
16. Serological investigations for evidence of the infectious aetiology of rheumatoid arthritis
17. Proteus IgG antibodies and C-reactive protein in English, Norwegian and Spanish patients with rheumatoid arthritis
18. The Proteus mirabilis antibody levels in patients with rheumatoid arthritis
19. Cross-reactivity between HLA-DR4 and Proteus mirabilis
20. Sequence similarity between HLA-DR1 and DR4 subtypes associated with rheumatoid arthritis and Proteus/serratia membrane haemolysins
21. Antibody to a specific HLA-DRβ1 sequence in Japanese patients with rheumatoid arthritis
22. Shared amino acid sequences between major histocompatibility complex class II glycoproteins, type XI collagen and Proteus mirabilis in rheumatoid arthritis
23. Increased serum and synovial antibodies to immunoselected peptides in patients with rheumatoid arthritis
24. Theoretical models to explain the association of HLA-B27 with ankylosing spondylitis
25. Is rheumatoid arthritis a form of reactive arthritis?
26. Rheumatoid arthritis as a reactive arthritis to Proteus infection: Prospects for therapy
27. Correlation between anti-Proteus antibodies and isolation rates of P. mirabilis in rheumatoid arthritis
28. Increased incidence of urinary tract infection in patients with rheumatoid arthritis and secondary Sjogren's syndrome
29. Site of infection in acute urinary tract infection in general practice
30. Antimicrobial therapy for rheumatoid arthritis
31. Antibiotic sensitivity and Proticine typing of Proteus mirabilis strains association with rheumatoid arthritis
32. Infections of the upper urinary tract
33. Decrease in anti-Proteus mirabilis but not anti-Escherichia coli antibody levels in rheumatoid arthritis patients treated with fasting and a one year vegetarian diet
34. An examination of the anti-adherence activity of cranberry juice on urinary and non-urinary bacterial isolates
35. Inhibitory activity of cranberry juice on adherence of type I and type P fimbriated Escherichia coli to eucaryotic cells
36. Reduction of bacteriuria and pyuria after ingestion of cranberry juice
37. Experiments with induced bacteriuria, vesical emptying and bacterial growth on the mechanism of bladder defence to infection
38. Management of urinary tract infection
39. Urease: The primary cause of infection-induced urinary stones
40. Ciprofloxacin and rheumatoid arthritis - Lack of effect