Effects of adenosine on extravascular lung water content in endotoxemic pigs

Critical Care Medicine

Volumn 29, Issue 12, 2001, Pages 2371-2376

  Kutzsche, S ^a   Lyberg, T ^a   Bjertnaes, L J ^a  

^a ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

Author keywords

Adenosine; Endothelin 1; Endotoxin; Extravascular lung water; Microvascular permeability; Microvascular pressure; Pigs

Indexed keywords

ADENOSINE; ENDOTHELIN 1; ENDOTOXIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD LEVEL; BLOOD PRESSURE; CONTROLLED STUDY; ENDOTOXEMIA; EXTRAVASATION; EXTRAVASCULAR SPACE; FEMALE; GAS EXCHANGE; LUNG FLUID; LUNG HEMODYNAMICS; MALE; NONHUMAN; PRIORITY JOURNAL; SWINE;

EID: 0035678124     PISSN: 00903493     EISSN: None     Source Type: Journal    
DOI: 10.1097/00003246-200112000-00021     Document Type: Article

References (38)

1. Increased sheep lung vascular permeability caused by Escherichia coli endotoxin
2. A porcine model of early adult respiratory distress syndrome induced by endotoxaemia
3. Adenosine, an endogenous anti-inflammatory agent
4. Cardiovascular effects of adenosine
5. Vascular endothelial and smooth muscle cells in culture selectively release adenine nucleotides
6. Adenosine: Supplementary considerations about activity and use
7. Hypoxic pulmonary vasoconstriction in the adult respiratory distress syndrome
8. Adenosine modulates vascular resistance and fluid filtration in isolated rat lungs
9. Adenosine protects ultrastructure of isolated rat lungs against fat emulsion injury
10. Adenosine produces pulmonary vasoconstriction in sheep. Evidence for thromboxane A2/prostaglandin endoperoxide-receptor activation
11. Endothelin-1-induced increases in microvascular permeability in isolated, perfused rat lungs requires leukocytes and plasma
12. Sustained effects of endothelin-1 on rabbit, dog, and rat pulmonary circulations
13. Effect of aminoguanidine on lung fluid filtration after endotoxin in awake sheep
14. Endothelin and hemodynamic responses to superior mesenteric artery occlusion shock and hemorrhagic shock in pigs
15. Pulmonary capillary pressure and filtration coefficient in the isolated perfused lung
16. Vascular resistance and Kf in normal and PMA-injured rabbit lungs: Effects of adenosine
17. The role of polymorphonuclear leukocytes in the pulmonary dysfunction induced by complement activation
18. Effects of endotoxemia on the sheep lung microvascular membrane: A two-pore theory
19. Physiological and pharmacological evidence for the regulation of permeability
20. Effects of adenosine on the functions of circulating polymorphonuclear leukocytes during hyperdynamic endotoxemia
21. Acting via A2 receptors, adenosine inhibits the upregulation of Mac-1 (Cd11b/CD18) expression on FMLP-stimulated neutrophils
22. A1-adenosine receptor antagonists block endotoxin-induced lung injury
23. Acting via A2 receptors, adenosine inhibits the production of tumor necrosis factor-alpha of endotoxin-stimulated human polymorphonuclear leukocytes
24. Effects of adenosine on cardiopulmonary functions and oxygen-derived variables during endotoxemia
25. Nucleotide metabolism by endothelium
26. Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation
27. Haemodynamic and metabolic effects of infused adenosine in man
28. Effect of infused adenosine on cardiac output and systemic resistance in normal subjects
29. Controlled endotoxinemia in pigs. A suitable model for in vivo studies of some haemodynamic, humoral and cellular reactions
30. Cardiac dysfunction after acute endotoxin administration in conscious sheep
31. Right heart function and endotoxemia in animals
32. Effect of adenosine on pulmonary circulation of rabbits
33. Adenosine-induced vasodilation: Receptor characterization in pulmonary circulation
34. Release of endothelin-like immunoreactivity in relation to neuropeptide Y and catecholamines during endotoxin shock and asphyxia in the pig
35. Increased plasma and pulmonary lymph levels of endothelin during endotoxin shock
36. Elevation of plasma endothelin concentrations during endotoxin shock in dogs
37. Impact of endothelin-1 in endotoxin-induced pulmonary vascular reactions
38. Endothelin-1: Demonstration of potent effects on the microcirculation of humans and other species