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Volumn 36, Issue 12, 2001, Pages 1287-1293
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Phase I metabolism of ganstigmine. Rat, dog, monkey and human liver microsomal extracts investigated by liquid chromatography electrospray tandem mass spectrometry
a
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Author keywords
Acetylcholinesterase inhibitor; Alzheimer; Drug metabolism; Electrospray ionization; Microsomes
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Indexed keywords
ENZYME INHIBITION;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
MASS SPECTROMETRY;
METABOLITES;
MOLECULAR BIOLOGY;
ELECTROSPRAY;
METABOLISM;
CHOLINESTERASE INHIBITOR;
DRUG METABOLITE;
GANSTIGMINE;
GENESEROLINE;
UNCLASSIFIED DRUG;
ANIMAL CELL;
ARTICLE;
CONTROLLED STUDY;
DEMETHYLATION;
DOG;
DRUG METABOLISM;
DRUG STRUCTURE;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN CELL;
HYDROXYLATION;
INCUBATION TIME;
LIVER MICROSOME;
MALE;
MONKEY;
NONHUMAN;
PRIORITY JOURNAL;
RAT;
TANDEM MASS SPECTROMETRY;
ALKALOIDS;
ALZHEIMER DISEASE;
ANIMALS;
CARBAMATES;
CHOLINESTERASE INHIBITORS;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
DOGS;
HUMANS;
HYDROXYLATION;
MACACA FASCICULARIS;
MALE;
MASS SPECTROMETRY;
METHYLATION;
MICROSOMES, LIVER;
OXIDATION-REDUCTION;
RATS;
RATS, SPRAGUE-DAWLEY;
SPECIES SPECIFICITY;
CANIS FAMILIARIS;
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EID: 0035677986
PISSN: 10765174
EISSN: None
Source Type: Journal
DOI: 10.1002/jms.228 Document Type: Article |
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Times cited : (5)
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References (13)
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