Limited-sampling strategy models for estimating the pharmacokinetic parameters of 4-methylaminoantipyrine, an active metabolite of dipyrone

Brazilian Journal of Medical and Biological Research

Volumn 34, Issue 11, 2001, Pages 1475-1485

  Suarez Kurtz, G ^a,b   Ribeiro, F M ^a   Estrela, R C E ^a   Vicente, F L ^a,b   Struchiner, C J ^a  

^a INSTITUTO NACIONAL DE CÂNCER   (Brazil)

^b Instituto de Dermatologia Prof Rubem David Azulay   (Brazil)

Author keywords

4 Methylaminoantipyrine; Bioequivalence; Dipyrone; Limited sampling models; Pharmacokinetics

Indexed keywords

DIPYRONE; DRUG METABOLITE; NEOSALDINA; NORAMIDOPYRINE;

ACCURACY; ADULT; AREA UNDER THE CURVE; ARTICLE; BIOEQUIVALENCE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG FORMULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PREDICTION; RANDOMIZED CONTROLLED TRIAL; REGRESSION ANALYSIS; SAMPLING; STATISTICAL MODEL; VALIDATION PROCESS; VOLUNTEER;

EID: 0035676658     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2001001100017     Document Type: Article

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