Effects of trimetazidine on altered functions of rat kidney mitochondria induced by cyclosporine;Effets de la trimétazidine sur les perturbations des fonctions mitochondriales de reins de rat induites par la ciclosporine A

Therapie

Volumn 56, Issue 5, 2001, Pages 583-587

  Simon, N ^a   Morin, C ^a   Bruguerolle, B ^a   Tillement, J P ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Ciclosporine A; Mitochondria; Nephrotoxicity; Trimetazidine

Indexed keywords

CYCLOSPORIN A; TRIMETAZIDINE;

ANIMAL CELL; ANIMAL TISSUE; CALCIUM TRANSPORT; CONFERENCE PAPER; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DRUG ANTAGONISM; NEPHROTOXICITY; NONHUMAN; OPTICAL DENSITY; OXIDATIVE PHOSPHORYLATION; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; SPECTROPHOTOMETRY;

ANIMALS; CALCIUM; CYCLOSPORINE; KIDNEY; MALE; MITOCHONDRIA; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; TRIMETAZIDINE; VASODILATOR AGENTS;

EID: 0035676621     PISSN: 00405957     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (15)

1. Cyclosporine
2. Cyclosporine-associated chronic nephropathy
3. The relative effects of FK506 and cyclosporine on short- and long-term kidney graft survival
4. Médiateurs impliqués dans la néphrotoxicité de la ciclosporine A
5. Role of mitochondria in Parkinson's disease
6. Findings in kidney transplant after treatment with cyclosporine
7. Influence of cyclosporin A on the respiration of isolated rat kidney mitochondria
8. Prednisolone and azathioprine worsen the cyclosporine A-induced oxidative phosphorylation decrease of kidney mitochondria
9. Glucocorticoids decrease cytochrome c oxidase activity of isolated rat kidney mitochondria
10. MicroPharm-K, a microcomputer interactive program for the analysis and simulation of pharmacokinetic processes
11. Action of cyclosporine on mitochondrial calcium fluxes
12. Cyclosporin A augments vasoconstrictor-induced rise in intracellular free calcium in rat renal mesangial cells
13. Inhibition of rat cerebral mitochondrial respiration by cyclosporins A, D, and G and restoration with trimetazidine
14. Regulation of the permeability transition pore, a voltage-dependent mitochondrial channel inhibited by cyclosporin A
15. Trimetazidine reverses calcium accumulation and impairment of phosphorylation induced by cyclosporine A in isolated rat liver mitochondria