Cibenzoline, an ATP-sensitive K+ channel blocker, binds to the K+-binding site from the cytoplasmic side of gastric H+, K+-ATPase

British Journal of Pharmacology

Volumn 134, Issue 8, 2001, Pages 1655-1662

  Tabuchi, Yoshiaki ^a   Yashiro, Hiroaki ^a   Hoshina, Satomi ^a   Asano, Shinji ^a   Takeguchi, Noriaki ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Cibenzoline; Hog gastric vesicle; Proton uptake

Indexed keywords

8 BENZYLOXY 2 METHYLIMIDAZO[1,2 A]PYRIDINE 3 ACETONITRILE; ADENOSINE TRIPHOSPHATASE (POTASSIUM); ADENOSINE TRIPHOSPHATE; CIBENZOLINE; POTASSIUM CHANNEL; POTASSIUM ION; PROTON;

ANIMAL CELL; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DRUG ACTIVITY; DRUG BINDING; DRUG MECHANISM; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME INHIBITION; HEART ARRHYTHMIA; HUMAN; HUMAN CELL; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; STOMACH;

ADENOSINE TRIPHOSPHATE; ANIMALS; BINDING SITES; CELL LINE; CELLS, CULTURED; CYTOPLASM; CYTOPLASMIC VESICLES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTRIC MUCOSA; H(+)-K(+)-EXCHANGING ATPASE; HUMANS; IMIDAZOLES; INHIBITORY CONCENTRATION 50; KIDNEY; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; RABBITS; SWINE; TRANSFECTION;

EID: 0035674498     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0704422     Document Type: Article

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