CPT-11 may provide therapeutic efficacy for esophageal squamous cell cancer and the effects correlate with the level of DNA topoisomerase I protein

Japanese Journal of Cancer Research

Volumn 92, Issue 12, 2001, Pages 1335-1341

  Nakajima, Yasuaki ^a   Miyake, Satoshi ^b   Nagai, Kagami ^a   Kawano, Tatsuyuki ^a   Iwai, Takehisa ^a  

^a Department of Surgery ^*  (Japan)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

CPT 11; DNA topoisomerase I; Esophageal squamous cell cancer; SN 38; Therapeutic efficacy

Indexed keywords

7 ETHYL 10 HYDROXYCAMPTOTHECIN; ANTINEOPLASTIC AGENT; DNA TOPOISOMERASE; DRUG METABOLITE; IRINOTECAN; MESSENGER RNA;

ARTICLE; CANCER CELL CULTURE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG EFFECT; DRUG EFFICACY; DRUG SYNTHESIS; ESOPHAGUS CANCER; ESOPHAGUS MUCOSA; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; METASTASIS INHIBITION; NORTHERN BLOTTING; PREOPERATIVE TREATMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SQUAMOUS CELL CARCINOMA; WESTERN BLOTTING;

BLOTTING, WESTERN; CAMPTOTHECIN; CELL DIVISION; DNA TOPOISOMERASES, TYPE I; DOSE-RESPONSE RELATIONSHIP, DRUG; ESOPHAGEAL NEOPLASMS; HUMANS; NEOPLASMS, SQUAMOUS CELL; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0035673428     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2001.tb02158.x     Document Type: Article

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