Effects of caffeine and its reactive metabolites theophylline and theobromine on the differentiating testis

Reproduction, Fertility and Development

Volumn 13, Issue 5-6, 2001, Pages 435-441

  Pollard, I ^a   Locquet, O ^a   Solvar, A ^a   Magre, S ^a  

^a MACQUARIE UNIVERSITY   (Australia)

Author keywords

Embryotoxicity; In vivo and in vitro testing methods; Sexual differentiation; Teratogenicity; Tissue and organ culture

Indexed keywords

CAFFEINE; THEOBROMINE; THEOPHYLLINE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; EXPLANT; FETUS; GERM CELL; IN VITRO STUDY; INTERSTITIUM; LEYDIG CELL; LIVER; MALE; NONHUMAN; PLACENTA; PREGNANCY; RAT; SEMINIFEROUS TUBULE; SERTOLI CELL; TESTIS DEVELOPMENT; TOXICITY;

ANIMALIA;

EID: 0035673161     PISSN: 10313613     EISSN: None     Source Type: Journal    
DOI: 10.1071/rd01018     Document Type: Article

References (21)

1. Placental transfer and fetal disposition of caffeine and its immediate metabolites in the 20-day pregnant rat: Function of dose
2. Initial phases of the rat testis differentiation in vitro
3. Fine structural localization of 3β-hydroxysteroid dehydrogenase in rat corpus luteum
4. 'Caffeine'
5. Xenobiotic metabolizing enzyme activities in rat, mouse, monkey, and human testes
6. Technique for investigation of sex chromatin in amniotic membrane of rat fetuses
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8. Use of human cumulus granulosa cells for in vitro screening of reproductive toxicants
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12. HPLC separation of theophylline, paraxanthine, theobromine, caffeine and other caffeine metabolites in biological fluids
13. Review of the genetic effects of caffeine
14. Action du serum de foetus de veau sur la differentiation in vitro ou le maintien des cordons seminiferes du testicule du foetus de rat
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17. Increases in plasma concentrations of steroids in the rat after the administration of caffeine: Comparison with plasma disposition of caffeine
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21. Accumulation of theophylline, theobromine and paraxanthine in the fetal rat brain following a single oral dose of caffeine