Characteristics of bone morphogenetic protein-induced chondroid bone: Histochemical, immunohistochemical and in situ hybridization examinations

Journal of International Medical Research

Volumn 29, Issue 6, 2001, Pages 480-487

  Kawakami, T ^a   Kawai, T ^b   Kimura, A ^a   Hasegawa, H ^a   Tsujigiwa, H ^c   Gunduz, M ^c   Nagatsuka, H ^c   Nagai, N ^c  

^a MATSUMOTO DENTAL UNIVERSITY   (Japan)

^b AICHI GAKUIN UNIVERSITY   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Bone matrix; Bone morphogenetic protein; Chondroid bone; Immunohistochemistry; In situ hybridization; MRNA; Ossification

Indexed keywords

BONE MORPHOGENETIC PROTEIN; COLLAGEN TYPE 1; COLLAGEN TYPE 2; MATRIX PROTEIN; MESSENGER RNA; OSTEOCALCIN; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARTILAGE; CONTROLLED STUDY; ENCHONDRAL OSSIFICATION; HISTOCHEMISTRY; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; MALE; MEDICAL RESEARCH; MOUSE; NONHUMAN; PROTEIN LOCALIZATION;

EID: 0035670510     PISSN: 03000605     EISSN: None     Source Type: Journal    
DOI: 10.1177/147323000102900603     Document Type: Article

References (16)

1. Bone: Formation by autoinduction
2. Transchondroid bone formation displayed in BMP-induced heterotopic osteogenesis
3. Bone morphogenetic protein (BMP) and bone formation
4. Pathological examination of transchondroid bone formation induced by bone morphogenetic protein
5. Squalane as a possible carrier of bone morphogenetic protein
6. Gene expression of bone matrix protein mRNA during BMP induced chondrogenesis and osteogenesis by in situ hybridization
7. Immunohistochemical study of heterotopic cartilage-bone formation induced by BMP-FGM
8. Histopathological and immunohistochemical study of heterotopic chondro-osseous tissue formation induced by S-200 BMP
9. BMPs induce direct bone formation in ectopic sites independent of endochondral ossification in vivo
10. Two distinctive BMP-carriers induced zonal chondrogenesis and membranous ossification, respectively; geometrical factors of matrices for cell-differentiation
11. Evaluation of heterotopic bone formation induced by squalane and bone morphogenetic protein composite
12. Three modes of ossification during distraction osteogenesis in the rat
13. Osteogenic differentiation of hypertrophic chondrocytes involves asymmetric cell divisions and apoptosis
14. Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix
15. Transitions in collagen types during endochondral ossification in human growth cartilage
16. Expression of transforming growth factor-beta peptide and its mRNA in chondrocytes in the early phase of BMP-induced heterotopic 'transchondroid bone formation'