Synaptic activation of a presynaptic kainate receptor facilitates AMPA receptor-mediated synaptic transmission at hippocampal mossy fibre synapses

Neuropharmacology

Volumn 41, Issue 8, 2001, Pages 907-915

  Lauri, Sari E ^a   Delany, Caroline ^a   Clarke, Vernon R J ^a   Bortolotto, Zuner A ^a   Ornstein, Paul L ^b   Isaac, John ^a   Collingridge, Graham L ^a  

^a UNIVERSITY OF BRISTOL   (United Kingdom)

^b ELI LILLY AND COMPANY   (United States)

Author keywords

APTA; Autoreceptor; Hippocampus; Kainate receptor; LY382884; Mossy fibres

Indexed keywords

1 (4 AMINOPHENYL) 3,4 DIHYDRO 4 METHYL 3 METHYLCARBAMOYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1 (4 AMINOPHENYL) 4 METHYL 7,8 METHYLENEDIOXY 5H 2,3 BENZODIAZEPINE; 1,2,3,4,4A,5,6,7,8,8A DECAHYDRO 6 (1H TETRAZOL 5 YLMETHOXYMETHYL) 3 ISOQUINOLINECARBOXYLIC ACID; 5,5 DIMETHYL 2 MORPHOLINEACETIC ACID; 6 (4 CARBOXYBENZYL) 1,2,3,4,4A,5,6,7,8,8A DECAHYDRO 3 ISOQUINOLINECARBOXYLIC ACID; ALPHA AMINO 5 TERT BUTYL 3 HYDROXY 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DECAHYDRO 6 [2 (1H TETRAZOL 5 YL)ETHYL] 3 ISOQUINOLINECARBOXYLIC ACID; GLUTAMIC ACID; KAINIC ACID RECEPTOR; LIGAND; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

ANIMAL TISSUE; ARTICLE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HIPPOCAMPUS; MOSSY FIBER; NONHUMAN; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; SYNAPTIC TRANSMISSION;

ANIMALS; EXCITATORY AMINO ACID AGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; ISOXAZOLES; MOSSY FIBERS, HIPPOCAMPAL; PROPIONATES; RATS; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; RECEPTORS, PRESYNAPTIC; SIGNAL TRANSDUCTION; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 0035669128     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00152-6     Document Type: Article

References (42)

1. The LTP Program: A data acquisition program for on-line analysis of long-term potentiation and other synaptic events
2. Kainate receptor gene expression in the developing rat brain
3. Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex
4. Neuropharmacology of AMPA and kainate receptors
5. Structure activity studies of aryl-spaced decahydroisoquinoline-3-carboxylic acid AMPA receptor antagonists
6. Kainate receptors are involved in synaptic plasticity
7. Kainate receptors mediate a slow postsynaptic current in hippocampal CA3 neurons
8. Regulation of glutamate release by presynaptic kainate receptors in the hippocampus
9. Kainate receptors: Subunits, synaptic localization and function
10. A hippocampal GluR5 kainate receptor regulating inhibitory synaptic transmission
11. Identification of the kainate receptor subunit underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus
12. Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus
13. B autoreceptors regulate the induction of LTP
14. Kainate receptor-mediated presynaptic inhibition at the mouse hippocampal mossy fibre synapse
15. Effects of folic and kainic acids on synaptic responses of hippocampal neurones
16. Modulation of fast synaptic transmission by presynaptic ligand-gated cation channels J
17. Kinetics and activation of postsynaptic kainate receptors at thalamocortical synapses: Role of glutamate clearance
18. A critical role of a facilitatory presynaptic kainate receptor in mossy fibre LTP
19. 3H]kainic acid binding sites in rat CNS as determined by autoradiography
20. Presynaptic receptors
21. Altered synaptic physiology and reduced susceptibility to kainate-induced seizures in GluR6-deficient mice
22. Intraventricular kainic acid preferentially destroys hippocampal pyramidal cells
23. Neurobiology-kainate receptors and synaptic plasticity
24. Decahydroisoquinolines: Novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia
25. A high-affinity presynaptic kainate-type glutamate receptor facilitates glutamate exocytosis from cerebral cortex nerve terminals (synaptosomes)
26. Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cord
27. Kainate binding sites in hippocampal mossy fibres: Localisation and plasticity
28. Kainic acid produces depolarisation of CA3 tyramidal cells in the vitro hippocampal slice
29. Kainate receptor modulation of GABA release involves a metabotropic function
30. Distinct short-term plasticity at two excitatory synapses in the hippocampus
31. Use-dependent increases in glutamate concentration activate presynaptic metabotropic glutamate receptors
32. Synaptic activation of presynaptic kainate receptors on hippocampal mossy fiber synapses
33. Presynaptic kainate receptor mediation of frequency facilitation at hippocampal mossy fibre synapses
34. Physiological activation of presynaptic metabotropic glutamate receptors increases intracellular calcium and glutamate release
35. Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat
36. On the relationship between kainic acid-induced epileptiform activity and hippocampal neuronal damage
37. The synaptic activation of the GluR5 subtype of kainate receptor in area CA3 of the rat hippocampus
38. The GluR5 subtype of kainate receptor regulates excitatory synaptic transmission in areas CA1 and CA3 of the rat hippocampus
39. The synaptic activation of kainate receptors in area CA3 of rat hippocampal slices
40. The synaptic activation of kainate receptors
41. Excitatory amino acid transmitters
42. Cellular and synaptic basis of kainic acid-induced hippocampal epileptiform activity