Early death and severe lymphopenia caused by ubiquitous expression of the Rag1 and Rag2 genes in mice

European Journal of Immunology

Volumn 31, Issue 12, 2001, Pages 3763-3772

  Barreto, Vasco ^a,b   Marques, Rute ^a   Demengeot, Jocelyne ^a  

^a INSTITUTO GULBENKIAN DE CIÊNCIA   (Portugal)

^b INSTITUT PASTEUR   (France)

Author keywords

Accessibility; Gene rearrangement; Lymphocyte; Rag; Rodent

Indexed keywords

IMMUNOGLOBULIN; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN J CHAIN; IMMUNOGLOBULIN KAPPA CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; IMMUNOGLOBULIN V CHAIN; RAG1 PROTEIN; RAG2 PROTEIN; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; CELL CYCLE; CELL LINEAGE; CELL MATURATION; CELL SPECIFICITY; CONTROLLED STUDY; DEATH; DISEASE SEVERITY; DNA REPAIR; DNA STRAND BREAKAGE; GENE MUTATION; GENETIC COMPLEMENTATION; GROWTH RETARDATION; LYMPHOCYTE; LYMPHOCYTE COUNT; LYMPHOCYTOPENIA; LYMPHOPOIESIS; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REGULATORY MECHANISM; T LYMPHOCYTE; THYMOCYTE; TRANSGENIC MOUSE;

ALLELES; ANIMALS; DNA-BINDING PROTEINS; GENES, RAG-1; GROWTH DISORDERS; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOCYTE COUNT; LYMPHOPENIA; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; TRANSGENES;

EID: 0035667196     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-4141(200112)31:12<3763::AID-IMMU3763>3.0.CO;2-Y     Document Type: Article

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