Role of iron-dextran on 7,12-dimethylbenz(a) anthracene-initiated and croton oil-promoted cutaneous tumorigenesis in normal and pregnant mice

Human and Experimental Toxicology

Volumn 20, Issue 9, 2001, Pages 471-476

  Rezazadeh, H ^a  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Croton oil; DMBA; Iron overload; Pregnancy; Skin tumorigenesis

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CROTON OIL; IRON DEXTRAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER INCIDENCE; CANCER STAGING; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DRUG TISSUE LEVEL; FEMALE; IRON OVERLOAD; MALE; MOUSE; MOUSE STRAIN; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; RECORDING; SKIN CARCINOGENESIS; SKIN PAPILLOMA; TUMOR PROMOTION;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; CARCINOGENS; CARCINOMA, SQUAMOUS CELL; CROTON OIL; FEMALE; IRON OVERLOAD; IRON-DEXTRAN COMPLEX; MALE; MICE; PAPILLOMA; PREGNANCY; PREGNANCY COMPLICATIONS, NEOPLASTIC; SKIN; SKIN NEOPLASMS;

ANIMALIA; CROTON;

EID: 0035666287     PISSN: 09603271     EISSN: None     Source Type: Journal    
DOI: 10.1191/096032701682693044     Document Type: Article

References (21)

1. Baker SI. Nutritional anemia a major controlable health problem. Bull WHO 1978; 56: 659-675.
2. Expert scientific working group. Summary of a report on assessment of the iron nutritional status of the United States population. Am J Clin Nutr 1985; 42: 318-330.
3. International nutritional anemia consultative group. Iron deficiency in infancy and childhood. Report prepared by Dallman PR, Simmes MA. New York and Washington. The nutrition WHO foundation, 1979.
4. Cook JD, Finch CA. Assessing iron status of a population. Am J Nutr 1979; 32: 2115-2119.
5. Reizenstein P. Iron, free radical and cancer. Med Oncol Tumor Pharmacother 1991; 8: 291-300.
6. Singh M, et al. Effect of excess dietary iron on the promotion stage of 1-methyl-1-nitrosourea-induced mammary carcinogenesis: pathogenic characteristic and distribution of iron. Carcinogenesis 1994; 15: 1567-1570.
7. Gordeuk VR, Bacon BR, Brittenham GM. Iron overload causes and consequences. Annu Rev Nutr 1987; 7: 485-503.
8. Bothwell TH, Seftel H, Jacobs P, Torrance JD, Baumslag N. Iron overload in Bantu subjects. Studies on availability of iron overload in Bantu beer. Am J Clin Nutr 1964; 14: 47-51.
9. Gordeuk VR, Boyd RD, Brittenham GM. Dietary iron overload persist in rural sub-Saharan Africa. Lancet 1986; 1: 1310-1313.
10. Stevens RG, et al. Moderate elevation of body iron level and increased risk of cancer occurrence and death. Int J Cancer 1994; 56: 364-369.
11. Selby JV, Friedman GD. Epidemiologic evidence of an association between body iron stores and risk of cancer. Int J Cancer 1988; 41: 677-682.
12. Rezazadeh H, Athar M. Evidence that iron overload promotes 7,12-dimethylbenz(a)anthracene-induced skin tumorigenesis in mice. Redox Hep 1997; 3: 303-309.
13. Rezazadeh H, Julka PK, Athar M. Iron overload augments 12,7-dimethylbenz(a)anthracene-initiated and 12-O-tetradecanoylphorbol-13-acetate-promoted skin tumorigenesis. Skin Pharmacol Appl Skin Physiol 1998; 11: 98-103.
14. Rezazadeh H, Athar M. Effect of iron overload on benzoyl peroxide-mediated tumor promotion in mouse skin. Cancer Lett 1998; 120: 135-142.
15. Beaton GH. Epidemiology of iron deficiency. In: Jacobs A, Worwood M (Eds), Iron in Biochemistry and Medicine. New York: Academic Press, 1974; pp. 477-528.
16. Council of foods and nutrition committee on iron deficiency. Iron deficiency in the United States. J Am Med Assoc 1968; 203: 407-412.
17. O'Connell JF, et al. Enhanced malignant progression of mouse skin tumors by the free-radical generator benzoyl peroxide. Cancer Res 1986; 40: 2863-2865.
18. Gaey CI, Ziboh VA, Marcelo CI, Voorhees JJ. Modulation of phospholipid metabolism in murine keratinocytes by tumor promoters 12-O-tetradecano-yl-13-phorbolacetate. J Invest Dermatol 1985; 85: 319-323.
19. Ford-Hutchinson AW. Arachidonic acid metabolism: enzymatic pathways. In: Ruzick T (Ed), Eicosanoids and the Skin. Boca Raton: CRC Press, 1990; p. 3.
20. Suny Y. Free radicals, antioxidant enzymes and carcinogenesis. Free Radical Biol Med 1990; 8: 583-599.
21. Cerutti P. Peroxidant states and tumor promotion. Science 1985; 227: 375-381.