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Volumn 8, Issue 42067, 2001, Pages 63-82

G-Actin Cleavage Parallels 2-5A-Dependent RNase L Cleavage in Peripheral Blood Mononuclear Cells—Relevance to a Possible Serum-Based Screening Test for Dysregulations in the 2-5A Pathway

Author keywords

2 5A pathway; 37 kDa 2 5A binding protein; apoptosis; calpain; CFS; chronic fatigue syndrome; G Actin; PBMC; RNase L; serum screening test

Indexed keywords

2',5' OLIGOADENYLIC ACID; CALPAIN; CASPASE 3; G ACTIN; RIBONUCLEASE; RIBONUCLEASE L; UNCLASSIFIED DRUG;

EID: 0035660239     PISSN: 10573321     EISSN: 15470660     Source Type: Journal    
DOI: 10.1300/J092v08n03_07     Document Type: Article
Times cited : (9)

References (32)
  • 1
    • 0018706198 scopus 로고
    • Natural occurrence of 2-5A in in-terferon-treated EMC virus-infected L cells
    • Williams BRG, Golgher RR, Brown RE, et al. Natural occurrence of 2-5A in in-terferon-treated EMC virus-infected L cells. Nature 1979; 282: 582 – 586.
    • (1979) Nature , vol.282 , pp. 582-586
    • Williams, B.R.G.1    Golgher, R.R.2    Brown, R.E.3
  • 2
    • 0028998705 scopus 로고
    • Catalytic cleavage of an RNA target by 2-5A antisense and R Nase L
    • Maitra RK, Li G, Xiao W, et al. Catalytic cleavage of an RNA target by 2-5A antisense and R Nase L. J. Biol. Chem. 1995; 270: 15071 – 15075.
    • (1995) J. Biol. Chem , vol.270 , pp. 15071-15075
    • Maitra, R.K.1    Li, G.2    Xiao, W.3
  • 3
    • 0028909072 scopus 로고
    • 2-5A-dependent R Nase molecules dimerize during ac-tivation by 2-5A
    • Dong B, Silverman RH. 2-5A-dependent R Nase molecules dimerize during ac-tivation by 2-5A. J. Biol. Chem. 1995; 270: 4133 – 4137.
    • (1995) J. Biol. Chem , vol.270 , pp. 4133-4137
    • Dong, B.1    Silverman, R.H.2
  • 5
    • 0031970114 scopus 로고    scopus 로고
    • Chronic fatigue syndrome: An update
    • Komaroff AL, Buchwald DS. Chronic fatigue syndrome: An update. Annu. Rev. Med. 1998; 49: 1 – 13.
    • (1998) Annu. Rev. Med , vol.49 , pp. 1-13
    • Komaroff, A.L.1    Buchwald, D.S.2
  • 6
    • 0029961385 scopus 로고    scopus 로고
    • Autoantibodies to nuclear envelope antigens in chronic fatigue syndrome
    • Konstantinov K, Von Miekecz A, Buchwald D, et al. Autoantibodies to nuclear envelope antigens in chronic fatigue syndrome. J. ClM. Invest. 1996; 98: 1888 – 1896.
    • (1996) J. ClM. Invest , vol.98 , pp. 1888-1896
    • Konstantinov, K.1    Von Miekecz, A.2    Buchwald, D.3
  • 7
    • 0025827369 scopus 로고
    • Chronic fatigue syndrome: Condition associated with immune activation
    • Landay AL, Jessop C, Lennette ET, et al. Chronic fatigue syndrome: Condition associated with immune activation. Lancet 1991; 338: 707 – 712.
    • (1991) Lancet , vol.338 , pp. 707-712
    • Landay, A.L.1    Jessop, C.2    Lennette, E.T.3
  • 9
    • 0029029040 scopus 로고
    • Chronic fatigue syn-drome: A clinical and laboratory study with a well matched control group
    • Swanink CMA., Vercoulen JHMM., Bleijenberg G., et al. Chronic fatigue syn-drome: A clinical and laboratory study with a well matched control group. J. Intern. Med. 1995; 237: 499 – 506.
    • (1995) J. Intern. Med , vol.237 , pp. 499-506
    • Swanink, C.M.A.1    Vercoulen, J.2    Bleijenberg, G.3
  • 10
    • 0031883887 scopus 로고    scopus 로고
    • CD4 T Lymphocytes from patients with chronic fatigue syndrome have decreased interferon-y production and increased sensi-tivity to dexamethasone
    • Visser J, Blauw B, Hinloopen B, et al. CD4 T Lymphocytes from patients with chronic fatigue syndrome have decreased interferon-y production and increased sensi-tivity to dexamethasone. J. Infect. Dis. 1998; 177: 451 – 454.
    • (1998) J. Infect. Dis , vol.177 , pp. 451-454
    • Visser, J.1    Blauw, B.2    Hinloopen, B.3
  • 11
    • 0028084853 scopus 로고
    • Upregulation of the 2-5A synthetase/R Nase L antiviral pathway associated with chronic fatigue syndrome
    • Suhadolnik RJ, Reichenbach NL, Hitzges P, et al. Upregulation of the 2-5A synthetase/R Nase L antiviral pathway associated with chronic fatigue syndrome. ClM. Infect. Dis. 1994; 18: S96–S 104.
    • (1994) ClM. Infect. Dis. , vol.18 , pp. S96S 104
    • Suhadolnik, R.J.1    Reichenbach, N.L.2    Hitzges, P.3
  • 12
    • 0028039192 scopus 로고
    • Changes in the 2-5A synthetase/R Nase L antiviral pathway in a controlled clinical trial with Poly(I)-Poly(C12U) in chronic fatigue syndrome
    • Suhadolnik RJ, Reichenbach NL, Hitzges P, et al. Changes in the 2-5A synthetase/R Nase L antiviral pathway in a controlled clinical trial with Poly(I)-Poly(C12U) in chronic fatigue syndrome. In Vivo 1994; 8: 599 – 604.
    • (1994) In Vivo , vol.8 , pp. 599-604
    • Suhadolnik, R.J.1    Reichenbach, N.L.2    Hitzges, P.3
  • 13
    • 0030863581 scopus 로고    scopus 로고
    • Biochemical evidence for a novel low molecular weight 2-5A-dependent R Nase L in chronic fatigue syndrome
    • Suhadolnik RJ, Peterson DL, O'Brien K, et al. Biochemical evidence for a novel low molecular weight 2-5A-dependent R Nase L in chronic fatigue syndrome. J. Interferon Cytokine Res. 1997; 17: 377 – 385.
    • (1997) J. Interferon Cytokine Res , vol.17 , pp. 377-385
    • Suhadolnik, R.J.1    Peterson, D.L.2    O'Brien, K.3
  • 14
    • 0033979461 scopus 로고    scopus 로고
    • A 37 kDa 2-5A binding protein as a potential biochemical marker for chronic fatigue syndrome
    • De Meirleir K, Bisbal C, Campine I, et al. A 37 kDa 2-5A binding protein as a potential biochemical marker for chronic fatigue syndrome. Am. J. Med. 2000; 108: 99 – 105.
    • (2000) Am. J. Med , vol.108 , pp. 99-105
    • De Meirleir, K.1    Bisbal, C.2    Campine, I.3
  • 15
    • 0031456383 scopus 로고    scopus 로고
    • Elevated apoptotic cell population in patients with chronic fatigue syndrome: The pivotal role of protein kinase RNA
    • Vojdani A, Ghoneum M, Choppa PC, et al. Elevated apoptotic cell population in patients with chronic fatigue syndrome: The pivotal role of protein kinase RNA. J. In-tern. Med. 1997; 242: 465 – 478.
    • (1997) J. In-tern. Med , vol.242 , pp. 465-478
    • Vojdani, A.1    Ghoneum, M.2    Choppa, P.C.3
  • 16
    • 0022990587 scopus 로고
    • Effects of serum vitamin-D-binding protein on actin in the presence of plasma gelsolin
    • Coue M, Constans J, Olomucki A. Effects of serum vitamin-D-binding protein on actin in the presence of plasma gelsolin. Eur. J. Biochem. 1986; 160: 273 – 277.
    • (1986) Eur. J. Biochem , vol.160 , pp. 273-277
    • Coue, M.1    Constans, J.2    Olomucki, A.3
  • 17
    • 0027510449 scopus 로고
    • Expression cloning of 2-5A-dependent RN Aase: A uniquely regulated mediator of interferon action
    • Zhou A, Hassel BA, Silverman RH. Expression cloning of 2-5A-dependent RN Aase: A uniquely regulated mediator of interferon action. Cell 1993; 72: 753 – 765.
    • (1993) Cell , vol.72 , pp. 753-765
    • Zhou, A.1    Hassel, B.A.2    Silverman, R.H.3
  • 19
    • 0028088153 scopus 로고
    • Calpain: New perspectives in molecular di-versity and physiological-pathological involvement
    • Saido TC, Sorimachi H, Suzuki K. Calpain: New perspectives in molecular di-versity and physiological-pathological involvement. FASEB J. 1994; 8: 814 – 822.
    • (1994) FASEB J , vol.8 , pp. 814-822
    • Saido, T.C.1    Sorimachi, H.2    Suzuki, K.3
  • 20
    • 0033561495 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis
    • Mashima T, Naito M, Tsuruo T. Caspase-mediated cleavage of cytoskeletal actin plays a positive role in the process of morphological apoptosis. Oncogene 1999; 18: 2423 – 2430.
    • (1999) Oncogene , vol.18 , pp. 2423-2430
    • Mashima, T.1    Naito, M.2    Tsuruo, T.3
  • 21
    • 0022636956 scopus 로고
    • Gc (vitamin D-binding pro-tein) binds the 33.5 K tryptic fragment of actin
    • Goldschmidt-Clermont P, Allen RC, Nel AE, et al. Gc (vitamin D-binding pro-tein) binds the 33.5 K tryptic fragment of actin. Life Sci. 1986; 38: 735 – 742.
    • (1986) Life Sci , vol.38 , pp. 735-742
    • Goldschmidt-Clermont, P.1    Allen, R.C.2    Nel, A.E.3
  • 22
    • 0024579970 scopus 로고
    • Jr Interactions among serum vitamin D binding protein, monomeric actin, profilin and profilactin
    • Mc Leod JF, Kowalski MA, Haddad JG. Jr Interactions among serum vitamin D binding protein, monomeric actin, profilin and profilactin. J. Biol. Chem. 1989; 264: 1260 – 1267.
    • (1989) J. Biol. Chem , vol.264 , pp. 1260-1267
    • Mc Leod, J.F.1    Kowalski, M.A.2    Haddad, J.G.3
  • 23
    • 0030794883 scopus 로고    scopus 로고
    • Activation of the IFN-inducible enzyme R Nase L causes apoptosis of animal cells
    • Diaz-Guerra M, Rivas C, Esteban M. Activation of the IFN-inducible enzyme R Nase L causes apoptosis of animal cells. Virology 1997; 236: 354 – 363.
    • (1997) Virology , vol.236 , pp. 354-363
    • Diaz-Guerra, M.1    Rivas, C.2    Esteban, M.3
  • 24
    • 0030924144 scopus 로고    scopus 로고
    • A study of the interferon antiviral mechanism: Apoptosis activation by the 2-5A system
    • Caste Ili JC, Hassel BA, Wood KA, et al. A study of the interferon antiviral mechanism: Apoptosis activation by the 2-5A system. J. Exp. Med. 1997; 186: 967 – 972.
    • (1997) J. Exp. Med , vol.186 , pp. 967-972
    • Caste Ili, J.C.1    Hassel, B.A.2    Wood, K.A.3
  • 25
    • 0031969695 scopus 로고    scopus 로고
    • Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
    • Villa G, Henzel WJ, Sensenbrenner M, et al. Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis. J. Cell Sci. 1998; 111: 713 – 722.
    • (1998) J. Cell Sci , vol.111 , pp. 713-722
    • Villa, G.1    Henzel, W.J.2    Sensenbrenner, M.3
  • 26
    • 0030957458 scopus 로고    scopus 로고
    • Actin is cleaved during constitutive apoptosis
    • Brown SB, Bailey K, Savill J. Actin is cleaved during constitutive apoptosis. Biochem. J. 1997; 323: 233 – 237.
    • (1997) Biochem. J , vol.323 , pp. 233-237
    • Brown, S.B.1    Bailey, K.2    Savill, J.3
  • 27
    • 0030888898 scopus 로고    scopus 로고
    • Actin cleavage by CPP32/apopain dur-ing the development of apoptosis
    • Mashima T, Naito M, Noguchi K, et al. Actin cleavage by CPP32/apopain dur-ing the development of apoptosis. Oncogene 1997; 14: 1007 – 1012.
    • (1997) Oncogene , vol.14 , pp. 1007-1012
    • Mashima, T.1    Naito, M.2    Noguchi, K.3
  • 28
    • 0031024495 scopus 로고    scopus 로고
    • Resistance of actin to cleavage during apoptosis
    • Song Q, Wei T, Lees-Miller S, et al. Resistance of actin to cleavage during apoptosis. Proc. Nat. Acad. Sci. USA 1997; 94: 157 – 162.
    • (1997) Proc. Nat. Acad. Sci. USA , vol.94 , pp. 157-162
    • Song, Q.1    Wei, T.2    Lees-Miller, S.3
  • 29
    • 0034232037 scopus 로고    scopus 로고
    • The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling
    • Dustin ML, Cooper JA. The immunological synapse and the actin cytoskeleton: Molecular hardware for T cell signaling. Nature Immunol. 2000; 1: 23 – 29.
    • (2000) Nature Immunol , vol.1 , pp. 23-29
    • Dustin, M.L.1    Cooper, J.A.2
  • 30
    • 0033984699 scopus 로고    scopus 로고
    • The biology of chronic fatigue syndrome
    • Komaroff AL. The biology of chronic fatigue syndrome. Am. J. Med. 2000; 108: 169 – 171.
    • (2000) Am. J. Med , vol.108 , pp. 169-171
    • Komaroff, A.L.1
  • 31
    • 84886639954 scopus 로고
    • Accurate quanti-tation of native Gc in serum and estimation of endogenous Gc:G-actin complexes by rocket immunoelectrophoresis
    • Goldschmidt-Clermont PJ, Galbraith RM, Emerson DL, et al. Accurate quanti-tation of native Gc in serum and estimation of endogenous Gc:G-actin complexes by rocket immunoelectrophoresis. Clin. Chim. Acta 1985; 148: 173 – 183.
    • (1985) Clin. Chim. Acta , vol.148 , pp. 173-183
    • Goldschmidt-Clermont, P.J.1    Galbraith, R.M.2    Emerson, D.L.3
  • 32
    • 0023257817 scopus 로고
    • Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein)
    • Young WO, Goldschmidt-Clermont P, Emerson DL, et al. Correlation between extent of liver damage in fulminant hepatic necrosis and complexing of circulating group-specific component (vitamin D-binding protein). J. Lab. Clin. Med. 1987; 110: 83 – 90.
    • (1987) J. Lab. Clin. Med , vol.110 , pp. 83-90
    • Young, W.O.1    Goldschmidt-Clermont, P.2    Emerson, D.L.3


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