Fatty acid specificity of hormone-sensitive lipase: Implication in the selective hydrolysis of triacylglycerols

Journal of Lipid Research

Volumn 42, Issue 12, 2001, Pages 2049-2057

  Raclot, Thierry ^a,b,d   Holm, Cecilia ^c   Langin, Dominique ^a  

^a CHU RANGUEIL   (France)

^b INSTITUT DE RECHERCHES SUBATOMIQUES   (France)

^c LUND UNIVERSITY   (Sweden)

^d CNRS   (France)

Author keywords

Adipose tissue; Fatty acid molecular structure; Lipid emulsion; Lipolysis

Indexed keywords

FATTY ACID; MONOUNSATURATED FATTY ACID; RECOMBINANT ENZYME; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; UNSATURATED FATTY ACID; VERY LONG CHAIN FATTY ACID;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; CHEMICAL STRUCTURE; EMULSION; ENZYME ACTIVITY; HORMONE SENSITIVITY; HYDROLYSIS; LIPOLYSIS; NONHUMAN; PRIORITY JOURNAL; RAT; TEMPERATURE SENSITIVITY;

ANIMALS; CHOLESTEROL ESTERASE; FATTY ACIDS, MONOUNSATURATED; FATTY ACIDS, UNSATURATED; HUMANS; HYDROLYSIS; KINETICS; RATS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TEMPERATURE; TRIGLYCERIDES;

EID: 0035658279     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. The lipid composition of adipose tissue
2. Effect of adrenaline, corticotropin, fasting, and diabetes on the composition of the long-chain fatty acids of rat epididymal fat
3. Adipose tissue lipases
4. Differential mobilization of white adipose tissue fatty acids according to chain length, unsaturation, and positional isomerism
5. Selectivity, of fatty acid mobilization: A general metabolic feature of adipose tissue
6. A role for hormonesensitive lipase in the selective mobilization of adipose tissue fatty, acids
7. Gene organization and primary structure of human hormone-sensitive lipase: Possible significance of a sequence homology with a lipase of Moraxella TA144, an antarctic bacterium
8. Domainstructure analysis of recombinant rat hormone-sensitive lipase
9. Human hormone-sensitive lipase: Expression and large-scale purification from a baculovirus/insect cell system
10. A simple method for the isolation and purification of total lipids from animal tissues
11. Thin-layer chromatography of human platelet phospholipids with fatty acid analysis
12. Preparation of fatty acid methyl esters and dimethyl acetals from lipids with boron fluoridemethanol
13. Peritz F-test: Basic program of a robust multiple comparison test for statistical analysis of all differences among group means
14. Positional specificity of hormone-sensitive lipase from rat adipose tissue
15. Mechanism of hormone-stimulated lipolysis in adipocytes: Translocation of hormone-sensitive lipase to the lipid storage droplet
16. Hydrolysis of chylomicron polyenoic fatty acid esters with lipoprotein lipase and hepatic lipase
17. The enteral bio-availability of eicosapentaenoic acid and docosahexaenoic acid is as good from ethyl esters as from glyceryl esters in spite of lower hydrolytic rates by pancreatic lipase in vitro
18. Lipases. II. Pancreatic lipase
19. Resistance of certain long-chain polyunsaturated fatty acids of marine oils to pancreatic lipase hydrolysis
20. Bacterial lipases
21. Stereo-selective hydrolysis of triglycerides by animal and microbial lipases
22. Adipose hormone-sensitive lipase preferentially releases polyunsaturated fatty acids from triglycerides
23. Effect of double bond position in octadecenoates upon hydrolysis by pancreatic lipase
24. Lipid biodynamics: New perspectives
25. News from the interface: The molecular structures of triacylglyceride lipases
26. General features of lipolysis: Reaction scheme, interfacial structure and experimental approaches
27. Lipid-lipid interactions as regulators of carboxylester lipase activity
28. Lateral lipid distribution is a major regulator of lipase activity. Implications for lipidmediated signal transduction
29. The effect of triacyl-sn-glycerol structure on the metabolism of chylomicrons and triacylglycerol-rich emulsions in the rat
30. Physical studies of d < 1.006 g/ml lymph lipoproteins from rats fed palmitate-rich diets
31. Physical characterization of lymph chylomicra and very low density lipoproteins from nonhuman primates fed saturated dietary fat
32. Analysis of the psychrotolerant property of hormone-sensitive lipase through site-directed mutagenesis
33. Selective mobilization of adipose tissue fatty acids during energy depletion in the rat
34. Release of individual fatty acids from human adipose tissue in vivo after an overnight fast
35. Selective release of human adipocyte fatty acids according to molecular structure
36. Fatty acid selectivity of a lipase purified from Vernonia galamensis seed
37. Interaction of rat hormone-sensitive lipase with adipocyte lipid-binding protein
38. Lipotransin: A novel docking protein for hormone-sensitive lipase
39. Altered insulin secretion associated with reduced lipolytic efficiency in aP2-/- mice
40. Targeted disruption of the adipocyte lipid-binding protein (aP2 protein) gene impairs fat cell lipolysis and increases cellular fatty acid levels
41. Perilipin, a major hormonally regulated adipocyte-specific phosphoprotein associated with the periphery of lipid storage droplets
42. Perilipin A increases triacylglycerol storage by decreasing the rate of triacylglycerol hydrolysis
43. On the control of lipolysis in adipocytes
44. Absence of perilipin results in leanness and reverses obesity in Lepr(db/db) mice