An in vitro screening system for characterizing the cleft palate-inducing potential of chemicals and underlying mechanisms

Reproductive Toxicology

Volumn 15, Issue 6, 2001, Pages 665-672

  Shimizu, Naoko ^a   Aoyama, Hiroaki ^a   Hatakenaka, Noriyuki ^a   Kaneda, Masahiro ^a   Teramoto, Shoji ^a  

^a INSTITUTE OF ENVIRONMENTAL TOXICOLOGY   (Japan)

Author keywords

5 fluorouracil; Cleft palate; Diphenylhydantoin; Hydrocortisone; PCNA; Retinoic acid; Suspension organ culture; TUNEL

Indexed keywords

CELL NUCLEUS ANTIGEN; FLUOROURACIL; HYDROCORTISONE; PHENYTOIN; RETINOIC ACID; TERATOGENIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CLEFT PALATE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; EXPLANT; FEMALE; GESTATIONAL AGE; GROWTH; MALE; NONHUMAN; ORGAN CULTURE; SCREENING; TERATOGENESIS; ANIMAL; CELL DIVISION; CHEMICALLY INDUCED DISORDER; CONGENITAL MALFORMATION; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; INSTITUTE FOR CANCER RESEARCH MOUSE; METABOLISM; MOUSE; ORGAN CULTURE TECHNIQUE; PALATE; PATHOLOGY; PRENATAL DEVELOPMENT;

ANIMALS; CELL DIVISION; CLEFT PALATE; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC AND FETAL DEVELOPMENT; FEMALE; FLUOROURACIL; HYDROCORTISONE; MALE; MICE; MICE, INBRED ICR; ORGAN CULTURE TECHNIQUES; PALATE; PHENYTOIN; TERATOGENS; TRETINOIN;

EID: 0035658148     PISSN: 08906238     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0890-6238(01)00175-7     Document Type: Article

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