Insulin antibodies are associated with lipoatrophy but also with lipohypertrophy in children and adolescents with type 1 diabetes

Experimental and Clinical Endocrinology and Diabetes

Volumn 109, Issue 8, 2001, Pages 393-396

  Raile, K ^a   Noelle, V ^a   Landgraf, R ^a   Schwarz, H P ^a  

^a UNIVERSITY HOSPITAL LEIPZIG   (Germany)

Author keywords

Children; Diabetes; GAD; IA; IA 2; Insulin; Lipoatrophy; Lipodystrophy; Lipohypertrophy

Indexed keywords

INSULIN ANTIBODY; INSULIN LISPRO; INSULIN ZINC SUSPENSION; SEMILENTE MC; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CONTROLLED STUDY; DISEASE ASSOCIATION; GLUCOSE BLOOD LEVEL; HUMAN; INJECTION SITE; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN TREATMENT; LIPOATROPHY; LIPODYSTROPHY; LIPOHYPERTROPHY; MAJOR CLINICAL STUDY; PRIORITY JOURNAL;

ADOLESCENT; ADULT; AUTOANTIBODIES; BODY MASS INDEX; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DIABETES MELLITUS, TYPE 1; GLUTAMATE DECARBOXYLASE; HISTOCOMPATIBILITY ANTIGENS CLASS II; HUMANS; INFANT; INSULIN; LIPODYSTROPHY;

EID: 0035658147     PISSN: 09477349     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2001-18991     Document Type: Article

References (10)

1. Severe lipoatrophy with human insulin: Successfully treated by CSII
2. Exposure to exogenous insulin promotes IgG1 and the T-helper 2-associated IgG4 responses to insulin but not to other islet autoantigens
3. Prevalence of lipohypertrophy in insulin-treated diabetic patients and predisposing factors
4. Computer programs and data sheets. Initiative on equality control of the German Working-Group on Pediatric Diabetology
5. Cutaneous manifestations of diabetes mellitus
6. Insulin-induced lipoatrophy: Evidence for an immune pathogenesis
7. Morphology of palpably abnormal injection sites and effects on absorption of isophane (NPH) insulin
8. Diabetic lipohypertrophy delays insulin absorption
9. Life-table analysis of progression to diabetes of anti-insulin antibody-positive relatives of individuals with type I diabetes