Interferon β affects retinal pigment epithelial cell proliferation via protein kinase C pathways

Ophthalmologica

Volumn 215, Issue 6, 2001, Pages 401-407

  Qiao, Hong ^a   Sakamoto, Taiji ^a,b   Hinton, David R ^b   Gopalakrishna, Rayudu ^b   Ishibashi, Tatsuro ^a   Ryan, Stephen J ^b   Inomata, Hajime ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Calphostin C; Interferon (IFN ); Protein kinase C (PKC); Retinal pigment epithelium (RPE); Subretinal neovascularization (SRN)

Indexed keywords

BETA INTERFERON; CALPHOSTIN; PROTEIN KINASE C; THYMIDINE; TRITIUM;

ARTICLE; CELL COUNT; CELL CULTURE; CELL MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOSOL; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; FETAL CALF SERUM; HUMAN; HUMAN CELL; PIGMENT EPITHELIUM; SIGNAL TRANSDUCTION;

CELL DIVISION; CELLS, CULTURED; DNA REPLICATION; ENZYME INHIBITORS; HUMANS; INTERFERON-BETA; NAPHTHALENES; PIGMENT EPITHELIUM OF EYE; PROTEIN KINASE C; SIGNAL TRANSDUCTION; UP-REGULATION;

EID: 0035655646     PISSN: 00303755     EISSN: None     Source Type: Journal    
DOI: 10.1159/000050897     Document Type: Article

References (20)

1. Effect of tecogalan sodium on angiogenesis in vitro by choroidal endothelial cells
2. Pathogenesis of laser-induced choroidal subretinal neovascularization
3. Migration of retinal pigment epithelium cells in vitro is regulated by protein kinase C
4. Subretinal neovascularization in the rat-induced by IRBP synthetic peptides
5. Vessel formation by choroidal endothelial cells in vitro is modulated by retinal pigment epithelial cells
6. Selective reduction of c-myc mRNA in Daudi cells by human β-interferon
7. The molecular heterogeneity of protein kinase C and its implications for cellular regulation
8. Protein kinase C: History and perspectives
9. The role of protein kinase C isoenzymes in the regulation of cell proliferation and differentiation
10. Growth factor-induced cytosolic calcium ion transients in cultured human retinal pigment epithelial cells
11. Intercellular gap formation induced by thrombin in confluent cultured bovine retinal pigment epithelial cells
12. Nitric oxide and nitric oxide-generating agents induce a reversible inactivation of protein kinase C activity and phorbol ester binding
13. Interferons induce xanthine dehydrogenase gene expression in L929 cells
14. Inhibitory effect of human fibroblast interferon (HuIFN-β) on the growth and invasive potential of cultured human melanoma cells in vitro
15. Effect of cytokines and prostaglandins on the growth of chick retinal pigment epithelial cells
16. Interferon beta-1 b inhibits gelatinase secretion and in vitro migration of human T cells: A possible mechanism for treatment efficacy in multiple sclerosis
17. Type I IFNs inhibit human dendritic cell IL-12 production and Th 1 cell development
18. Growth regulation of retinal pigment epithelial (RPE) cells in vitro
19. Involvement of the protein kinase pathway in melanin synthesis by chick retinal pigment epithelial cells
20. Interferons block protein kinase C-dependent but not -independent activation of Raf-1 and mitogen-activated protein kinases and mitogenesis in NlH 3T3 cells