Comparison of the responses of global tests of coagulation with molecular markers of neutrophil, endothelial, and hemostatic system perturbation in the baboon model of E. coli Sepsis: Toward a distinction between uncompensated overt DIC and compensated non-overt DIC

Thrombosis and Haemostasis

Volumn 86, Issue 6, 2001, Pages 1489-1494

  Wada, H ^a   Yamamuro, M ^a   Inoue, A ^a   Shiku, H ^a   Sakuragawa, N ^a   Redl, H ^a   Peer, G ^a   Taylor F B , Jr ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

Baboon; Disseminated intravascular coagulation; E. coli; Endothelium; Hemostasis; Sepsis

Indexed keywords

ANTIPLASMIN; ANTITHROMBIN; BIOCHEMICAL MARKER; ELASTASE; PLASMIN; THROMBIN; THROMBOMODULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BABOON; BLOOD CLOTTING TEST; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DISSEMINATED INTRAVASCULAR CLOTTING; ENDOTHELIUM; ENTEROBACTER INFECTION; HEMOSTASIS; HUMAN; MOLECULAR DYNAMICS; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; SEPSIS;

EID: 0035655008     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0037-1616753     Document Type: Article

References (23)

1. Disseminated intravascular coagulation and related syndromes: A clinical review
2. Pathophysiologic and biochemical events in disseminated intravascular coagulation: Dysregulation of procoagulant and anti-coagulant pathways
3. Criteria for diagnosis of DIC based on the analysis of clinical and laboratory findings in 345 DIC patients collected by the Research Committee on DIC in Japan
4. Outcome of disseminated intravascular coagulation in relation to the score when treatment was begun
5. Hemostatic study before onset of disseminated intravascular coagulation
6. Thrombin versus plasmin generation in disseminated intravascular coagulation associated with various disorders
7. Increased plasma soluble fibrin monomer levels in patients with disseminated intravascular coagulation
8. Plasma thrombomodulin as a marker of vascular disorders in thrombotic thrombocytopenic purpura
9. Thrombomodulin release in baboon sepsis: Its dependence on the dose of Escherichia coli and the presence of tumor necrosis factor
10. Poor outcome in disseminated intravascular coagulation or thrombotic thrombocytopenic purpura patients with severe vascular endothelial cell injuries
11. Studies of the natural history of the mechanism of the primate (baboon) response to Escherichia coli
12. Coagulation studies in hemolytic uremic syndrome and thrombotic thrombocytopenic purpura
13. C4b-binding protein exacerbates the host response to Escherichia coli
14. 2, a monoclonal antibody to the platelet GPIIb/IIIa receptor, protects against microangiopathic hemolytic anemia and microvascular thrombotic renal failure in baboons treated with C4b binding protein and a sublethal infusion of Escherichia coli
15. Retrospective description and experimental reconstitution of three different responses of the baboon to lethal E. coli
16. Endotoxemia in primate models
17. Detection of the "hyperdynamic state" of sepsis in the baboon during lethal E. coli infusion
18. Method for estimating fibrinogen concentration - Thrombin time test
19. Plasma elastase alpha, -antitrypsin and lactoferrin in sepsis: Evidence for neutrophils as mediators in fatal sepsis
20. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation
21. Peritonitis in the baboon: A primate model that simulates human sepsis