Synthesis and biological activity of 2-thioxo-[1H]-5-spirocyclohexylimidazo[4,3-b] quinazolone and 8-azaquinazolone derivatives

Phosphorus, Sulfur and Silicon and Related Elements

Volumn 173, Issue , 2001, Pages 105-113

  Hamad Elgazwy, Abdel Sattar S ^a   Azab, Mohamed E ^a  

^a Ain Shams University   (Egypt)

Author keywords

5 Spirocyclohexylimidazole 2,4 dithion; 8 azaquinazolone; Quinazolone; Thiohydantoin; aminocarboxylic acid

Indexed keywords

EID: 0035648832     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426500108045263     Document Type: Article

References (31)

1. R. Hazard, C. Jean, P. Chabrier and K. Smarzewaska, Compt. Med., 1949, 222, 1762.; Chem. Abstr. 1949, 43, 7585.
2. R. Hazard, C. Jean, P. Chabrier and K. Smarzewaska, Compt. Med., 1949, 222, 1762.; Chem. Abstr. 1949, 43, 7585.
3. S. Ajmera and P. C. Dandiya. Drugs Exp. Clin. Res. 1982, 8, 457-459.; Chem. Abstr. 1982, 97, 155954r.
4. S. Ajmera and P. C. Dandiya. Drugs Exp. Clin. Res. 1982, 8, 457-459.; Chem. Abstr. 1982, 97, 155954r.
5. J. R. Merchant and A. S. Gupta, Indian J. Chem. Sect. B, 1978, 16, 71-73.; Chem. Abstr. 1978, 88, 136520u.
6. J. R. Merchant and A. S. Gupta, Indian J. Chem. Sect. B, 1978, 16, 71-73.; Chem. Abstr. 1978, 88, 136520u.
7. G. N. Mahapatra, H. P. Das. Indian J. Chem. Sect. B,. 1979, 18, 257-261.
8. A. M. Kadry, E. H. Abdel-Al and H. A. Abdel-Fattah. Bull. Fac. Pharm. Cairo University 1991, 29, 21.
9. C. R. Mackerer, R. N. Saunder, J. R. Haettinger and M. A. Mohlman, J. Toxicol. Environ. Health 1977, 2, 1041.
10. D. F. Morrow and W. L. Matier, U.S. Pat. 1977, 4, 243, 681.; Chem. Abstr. 1982, 96, 34812p.
11. D. Binder and H. Ferber. Eur. Pat. 1987, 19, 173, 233.; Chem. Abstr. 1988, 108, 5853p.
12. H. Ferres, A. W. Tyrrell and G. R. Geen, Drugs Exp. Clin. Res 1982, 52, 964.; Chem. Abstr. 1982, 97, 163012x.
13. H. Ferres, A. W. Tyrrell and G. R. Geen, Drugs Exp. Clin. Res 1982, 52, 964.; Chem. Abstr. 1982, 97, 163012x.
14. W. G. Taylor and W. A. Remers, J. Med. Chem. 1975, 18, 307-310.
15. B. J. Kennedy, Cancer 1970, 26, 755-759.
16. J. Long and H. Todyays, Pol. J. Pharmacol. Pharm. 1976, 27, 211-214. , Chem. Abstr. 1976, 84, 17236p.
17. J. Long and H. Todyays, Pol. J. Pharmacol. Pharm. 1976, 27, 211-214. , Chem. Abstr. 1976, 84, 17236p.
18. K. Buechi, W. Kramer and P. Frohberger, Ger. Offen. 1975, 335, 020.; Chem. Abstr. 1975, 82, 170966e and 170967f.
19. G. Asato, G. Berkelhannaer and W. Gastrock, U.S. pat 1976, 3, 940, 411.; Chem. Abstr. 1976, 85, 5664e.
20. A. Sen Gupta and H. Missra, Indian J. Chem. Sect. B, 1979, 17B, 189-193.
21. El-Kafrawy, A.F., Yousset, A.S.; Abdel-Sattar S. Hamad and Hashem A.I., Egypt J. Pharm. Soc. 1993, 34, No. 1-3, pp. 159-170.
22. R. Bhamaria, R. Bellare and C. Deliwala, Indian J. Exp. Biol. 1986, 6, 62-65.
23. N. Biju-Hor, N. Xuong and Nam, Acad. Sci. 1954, 238, 295.
24. a) Ivin, B. A.; Rutkovskü, G. V., Smorygo, N.A., Frolova, G.M.; Zh. Org. Kim. (Russ) 1973, 9(11), 2405-11.;
25. b) Chubb, Francis L.; Edward, John T.; Can. J. Chem., 1981, 59, 2724-2728.;
26. Carrington, J. Chem. Soc., 1947, 681.;
27. Johnson and Scott, J. Amer. Chem. Soc., 1913, 35, 1130.
28. A.A. Hamed, A.I. Hashem, M.A. Salem and H.F. Madkour Egypt. J. Chem., 1986, 24, 89.
29. E. P. Abraham, Endeavour 1959, 18, 217.
30. Collins, C. H.; Microbiological methods, P. 89, Bulterworths press, London 1964.
31. Edwards, D.I. (Antimicrobial Drug action) the Macmillan. Press limited. 1980, p. 16-30.