Studies on the reactions of 2,3-diketopyrido[4,3,2-de] quinolines with aliphatic amines

Heterocyclic Communications

Volumn 7, Issue 2, 2001, Pages 107-112

  Shao, Huawu ^a   Ding, Qizhu ^a   Lown, J William ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035640309     PISSN: 07930283     EISSN: None     Source Type: Journal    
DOI: 10.1515/HC.2001.7.2.107     Document Type: Article

References (33)

1. T. F. Molinski, Chem. Rev. 93, 1825 (1993).
2. B. S. Davidson, Chem. Rev. 93, 1771 (1993)
3. P. J. Scheuer, Science 248, 173 (1990).
4. (a) L. A. McDonald, G. S. Eldridge, L. R. Barrows and C. M. Ireland, J. Med. Chem. 37, 3819 (1994);
5. (b). F. J. Schmitz, F. S. DeGuzman, M. B. Hossain, D. van der Helm, J. Org. Chem. 56, 804 (1991);
6. (c). N. S. Burres, S. S. Sazesh, G. P. Gunawardana and J. J. Clement, Cancer Res. 49, 5267 (1989);
7. (d). M. Alvarez and J. A. Joule, Heterocycles 34, 2385 (1992);
8. (f). M. A. Cuifolini, Y. C. Shen and J. Bishop, J. Am. Chem. Soc. 117, 12460 (1995)
9. (a). I. B. Taraporewala, J. W. Cessac, T. C. Chanh, A. V. Delgado, R. F. Schinazi, J. Med. Chem. 35, 2774 (1992);
10. (b). A. Plubrukarn and B. S. Davidson, J. Org. Chem. 63, 1657 (1998);
11. (c). M. A. Ciufolini and Y. C. Shen, Tetrahedron Lett. 36, 4709 (1995);
12. (d). C. E. Muller, U. Geis, B. Grahner, W. Lanzner and K. Egger, J. Med. Chem. 39, 2482 (1996)
13. (a). G. P. Gunawardana, S. Kohmoto, S. P. Gunasekera, O. J. Mcconnell and F. E. Koehn, J. Am. Chem. Soc. 110, 4856 (1988);
14. (b). G. P. Gunawardana, S. Kohmoto, N. S. Burres, Tetrahedron Lett. 30, 4359 (1989);
15. (c). C. J. Smith, D. Abbanat, V. S. Bernan, W. M. Maiese, M. Greenstein, J. Jompa, A. Tahir, C. M. Ireland, J. Nat. Prod. 63, 142 (2000);
16. (d). G. M. Nicholas, T. F. Molinski, J. Am. Chem. Soc. 122, 4011 (2000);
17. (e). L. L. Chen, T. F. Molinski, I. N. Pessah, J. Biol. Chem. 274, 32603 (1999);
18. (f). G. A. Charyulu, T. C. Mckee, C. M. Ireland, Tetrahedron Lett. 30, 4201 (1989)
19. T. M. Molinski and C. M. Ireland, J. Org. Chem. 54, 4256 (1989)
20. M. A. Ciufolini and N. E. Byrne, J. Am. Chem. Soc. 113, 8016 (1991)
21. J. Kobayashi, J. F. Cheng, M. R. Walchli, H. Nakamura, Y. Hirata, T. Sasaki and Y. Ohizumi, J. Org. Chem. 53, 1800 (1988)
22. S. J. Bloor and F. J. Schmitz, J. Am. Chem. Soc. 109, 6134 (1987); F. S. de Guzman, F. J. Schmitz, Tetrahedron Lett. 30, 1069 (1987)
23. S. J. Bloor and F. J. Schmitz, J. Am. Chem. Soc. 109, 6134 (1987); F. S. de Guzman, F. J. Schmitz, Tetrahedron Lett. 30, 1069 (1987)
24. (a). R. L. Zhao and J. W. Lown, Synth. Commun. 27, 2103 (1997);
25. (b). R. L. Zhao, B. Oreski and J. W. Lown, Bioorg. and Med. Chem. Lett. 6, 2169 (1996)
26. Q. Z. Ding, R. L. Zhao and J. W. Lown, Heterocycl. Commun. 3, 489 (1997)
27. (a). Q. Z. Ding and J. W. Lown, Heterocycl. Commun. 4, 125 (1998);
28. (b). Q. Z. Ding, K. Chichak and J. W. Lown, Current Medicinal Chemistry 6, 1 (1999);
29. (c). Q. Z. Ding and J. W. Lown, Heterocycl. Commun. 4, 535 (1998)
30. Q. Z. Ding and J. W. Lown, J. Org. Chem. 64, 7965 (1999)
31. Q. Z. Ding, G. F. Jia and J. W. Lown, Anti-Cancer Drug Design 15, 99 (2000)
32. H. W. Shao, Q. Z. Ding and J. W. Lown, Heterocycl. Commun., in press
33. 4Cl: C, 50.75; H, 3.28; N, 13.66; Found C, 50.92; H, 3.40; N, 13.81