Large-scale syntheses of FMOC-protected non-proteogenic amino acids: Useful building blocks for combinatorial libraries

Organic Process Research and Development

Volumn 5, Issue 4, 2001, Pages 445-449

  Dener, Jeffrey M ^a   Fantauzzi, Pascal P ^a   Kshirsagar, Tushar A ^a   Kelly, Daphne E ^a   Wolfe, Aaron B ^a  

^a ChemRx Advanced Technologies   (United States)

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EID: 0035638947     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op010204f     Document Type: Article

References (24)

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9. A related procedure has been reported that requires extractions with ethyl acetate: Milton, R. C.; Becker, E.; Milton, S. C. F.; Baxter, J. E. J.; Ellsorth, J. F. Int. J. Pept. Protein Res. 1987, 30, 431-432. See also: Ten Kortenaar, P. B. W.; Van Dijk, B. G.; Peeters, J. M.; Raaben, B. J.; Adams, P. J. H. M.; Tesser, G. I. Int. J. Pept. Protein Res. 1986, 27, 398-400.
10. A related procedure has been reported that requires extractions with ethyl acetate: Milton, R. C.; Becker, E.; Milton, S. C. F.; Baxter, J. E. J.; Ellsorth, J. F. Int. J. Pept. Protein Res. 1987, 30, 431-432. See also: Ten Kortenaar, P. B. W.; Van Dijk, B. G.; Peeters, J. M.; Raaben, B. J.; Adams, P. J. H. M.; Tesser, G. I. Int. J. Pept. Protein Res. 1986, 27, 398-400.
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23. The specific details for library synthesis involving these intermediates will be described in a separate publication.
24. In some cases complete dissolution of sodium sulfite was observed.