메뉴 건너뛰기




Volumn 18, Issue 2, 2001, Pages 149-158

Optimization of Large-Scale Chromatography of Proteins

Author keywords

Adsorption Chromatography; Column Productivity; Confocal Microscopy; Gel Filtration; Gel Media; Large Scale Chromatography; Optimisation; Protein Chromatography

Indexed keywords


EID: 0035611027     PISSN: 02561115     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02698452     Document Type: Article
Times cited : (12)

References (26)
  • 1
    • 0007133874 scopus 로고
    • Restricted Diffusion of Macromolecules through Agar-gel Membranes
    • Ackers, G. K. and Steere, R. L., "Restricted Diffusion of Macromolecules through Agar-gel Membranes," Biochim. Biophys. Acta, 59, 137 (1962).
    • (1962) Biochim. Biophys. Acta , vol.59 , pp. 137
    • Ackers, G.K.1    Steere, R.L.2
  • 4
    • 0003691546 scopus 로고    scopus 로고
    • Academic Press
    • As general references on large scale chromatography the following books and chapter, respectively, are recommended reading: Handbook of Process Chromatography, G. Sofer and L. Hagel, Academic Press (1997); Process Chromatography-A Practical Guide, G. Sofer and L.-E. Nyström, Academic Press, 1989; Process Chromatography-A Guide to Validation, G. Sofer and Lars-Erik Nyström, Academic Press, 1991; Large-scale Chromatography of Proteins, J.-C. Janson and P. Hedman, in A. Rechter (ed.) Advances in Biochemical Engineering, Springer Verlag, 25, 43 (1982).
    • (1997) Handbook of Process Chromatography
    • Sofer, G.1    Hagel, L.2
  • 5
    • 0003430248 scopus 로고
    • Academic Press
    • As general references on large scale chromatography the following books and chapter, respectively, are recommended reading: Handbook of Process Chromatography, G. Sofer and L. Hagel, Academic Press (1997); Process Chromatography-A Practical Guide, G. Sofer and L.-E. Nyström, Academic Press, 1989; Process Chromatography-A Guide to Validation, G. Sofer and Lars-Erik Nyström, Academic Press, 1991; Large-scale Chromatography of Proteins, J.-C. Janson and P. Hedman, in A. Rechter (ed.) Advances in Biochemical Engineering, Springer Verlag, 25, 43 (1982).
    • (1989) Process Chromatography-A Practical Guide
    • Sofer, G.1    Nyström, L.-E.2
  • 6
    • 0003430249 scopus 로고
    • Nyström, Academic Press
    • As general references on large scale chromatography the following books and chapter, respectively, are recommended reading: Handbook of Process Chromatography, G. Sofer and L. Hagel, Academic Press (1997); Process Chromatography-A Practical Guide, G. Sofer and L.-E. Nyström, Academic Press, 1989; Process Chromatography-A Guide to Validation, G. Sofer and Lars-Erik Nyström, Academic Press, 1991; Large-scale Chromatography of Proteins, J.-C. Janson and P. Hedman, in A. Rechter (ed.) Advances in Biochemical Engineering, Springer Verlag, 25, 43 (1982).
    • (1991) Process Chromatography-A Guide to Validation
    • Sofer, G.1    Lars-Erik2
  • 7
    • 0001941315 scopus 로고
    • Large-scale Chromatography of Proteins
    • A. Rechter (ed.) Springer Verlag
    • As general references on large scale chromatography the following books and chapter, respectively, are recommended reading: Handbook of Process Chromatography, G. Sofer and L. Hagel, Academic Press (1997); Process Chromatography-A Practical Guide, G. Sofer and L.-E. Nyström, Academic Press, 1989; Process Chromatography-A Guide to Validation, G. Sofer and Lars-Erik Nyström, Academic Press, 1991; Large-scale Chromatography of Proteins, J.-C. Janson and P. Hedman, in A. Rechter (ed.) Advances in Biochemical Engineering, Springer Verlag, 25, 43 (1982).
    • (1982) Advances in Biochemical Engineering , vol.25 , pp. 43
    • Janson, J.-C.1    Hedman, P.2
  • 11
    • 4243603471 scopus 로고
    • Chromatographic Separation According to Size of Macromolecules and Cell Particles on Columns of Agarose Suspensions
    • Hjertén, S., "Chromatographic Separation According to Size of Macromolecules and Cell Particles on Columns of Agarose Suspensions," Arch. Biochem. Biophys., 99, 466 (1962).
    • (1962) Arch. Biochem. Biophys. , vol.99 , pp. 466
    • Hjertén, S.1
  • 12
    • 0012542001 scopus 로고
    • The Preparation of Agarose Spheres for Chromatography of Molecules and Particles
    • Hjertén, S., "The Preparation of Agarose Spheres for Chromatography of Molecules and Particles," Biochim. Biophys. Acta, 79, 393 (1964).
    • (1964) Biochim. Biophys. Acta , vol.79 , pp. 393
    • Hjertén, S.1
  • 14
    • 0024494453 scopus 로고
    • Production Scale Purification of Biosynthetic Human Insulin by Reversed-Phase High-performance Liquid Chromatography
    • Kroeff, E. P., Owens, R. A., Campbell, E. L., Johnson, R. D. and Marks, H. I., "Production Scale Purification of Biosynthetic Human Insulin by Reversed-Phase High-performance Liquid Chromatography," J. Chromatogr., 461, 45 (1989).
    • (1989) J. Chromatogr. , vol.461 , pp. 45
    • Kroeff, E.P.1    Owens, R.A.2    Campbell, E.L.3    Johnson, R.D.4    Marks, H.I.5
  • 16
    • 0033590259 scopus 로고    scopus 로고
    • Visualizing Two Component Protein Diffusion in Porous Adsorbents by Confocal Scanning Laser Microscopy
    • Linden, T., Ljunglöf, A., Kula, M. R. and Thömmes, J., "Visualizing Two Component Protein Diffusion in Porous Adsorbents by Confocal Scanning Laser Microscopy," Biotechnol. Bioeng., 65, 622 (1999).
    • (1999) Biotechnol. Bioeng. , vol.65 , pp. 622
    • Linden, T.1    Ljunglöf, A.2    Kula, M.R.3    Thömmes, J.4
  • 17
    • 0032998971 scopus 로고    scopus 로고
    • Direct Visualisation of Plasmid DNA in Individual Chromatography Adsorbent Particles by Confocal Scanning Laser Microscopy
    • Ljunglöf, A., Bergvall, P., Bhikhabhai, R. and Hjorth, R., "Direct Visualisation of Plasmid DNA in Individual Chromatography Adsorbent Particles by Confocal Scanning Laser Microscopy," J. Chromatogr. A, 844, 129 (1999).
    • (1999) J. Chromatogr. A , vol.844 , pp. 129
    • Ljunglöf, A.1    Bergvall, P.2    Bhikhabhai, R.3    Hjorth, R.4
  • 18
    • 0034613419 scopus 로고    scopus 로고
    • Measurement of Ligand Distribution in Individual Adsorbent Particles Using Confocal Scanning Laser Microscopy and Confocal Micro-Raman Spectroscopy
    • Ljunglöf, A., Larsson, M., Knuuttila, K. G. and Lindgren, J., "Measurement of Ligand Distribution in Individual Adsorbent Particles Using Confocal Scanning Laser Microscopy and Confocal Micro-Raman Spectroscopy," J. Chromatogr. A, 893, 235 (2000).
    • (2000) J. Chromatogr. A , vol.893 , pp. 235
    • Ljunglöf, A.1    Larsson, M.2    Knuuttila, K.G.3    Lindgren, J.4
  • 19
    • 19244387159 scopus 로고    scopus 로고
    • Visualising Intraparticle Protein Transport in Porous Adsorbents by Confocal Microscopy
    • Ljunglöf, A. and Thömmes, J., "Visualising Intraparticle Protein Transport in Porous Adsorbents by Confocal Microscopy," J. Chromatogr. A, 813, 387 (1998).
    • (1998) J. Chromatogr. A , vol.813 , pp. 387
    • Ljunglöf, A.1    Thömmes, J.2
  • 20
    • 0343711002 scopus 로고
    • Industrial-scale Downstream Processing of Biotechnology Products
    • Naveh, D., "Industrial-scale Downstream Processing of Biotechnology Products," BioPharm, 5, 28 (1990).
    • (1990) BioPharm , vol.5 , pp. 28
    • Naveh, D.1
  • 21
    • 33748919316 scopus 로고
    • Gel Filtration: A Method for Desalting and Group Separation
    • Porath, J. and Flodin, P., "Gel Filtration: A Method for Desalting and Group Separation," Nature, 183, 1657 (1959).
    • (1959) Nature , vol.183 , pp. 1657
    • Porath, J.1    Flodin, P.2
  • 22
    • 27144507897 scopus 로고
    • Agar Derivatives for Chromatography, Electrophoresis and Gel Bound Enzymes. I. Desulphated and Reduced Cross-linked Agar and Agarose in Spherical Bead Form
    • Porath, J., Janson, J.-C. and Låås, T., "Agar Derivatives for Chromatography, Electrophoresis and Gel Bound Enzymes. I. Desulphated and Reduced Cross-linked Agar and Agarose in Spherical Bead Form," J. Chromatogr., 60, 167 (1971).
    • (1971) J. Chromatogr. , vol.60 , pp. 167
    • Porath, J.1    Janson, J.-C.2    Låås, T.3
  • 23
    • 0016851193 scopus 로고
    • Agar Derivatives for Chromatography, Electrophoresis and Gel-bound Enzymes. III. Rigid Agarose Gels Cross-linked with Divinyl Sulphone (DVS)
    • Porath, J., Låås, T. and Janson, J.-C., "Agar Derivatives for Chromatography, Electrophoresis and Gel-bound Enzymes. III. Rigid Agarose Gels Cross-linked with Divinyl Sulphone (DVS)," J. Chromatogr., 103, 49 (1975).
    • (1975) J. Chromatogr. , vol.103 , pp. 49
    • Porath, J.1    Låås, T.2    Janson, J.-C.3
  • 26
    • 0002419874 scopus 로고
    • Monodisperse Polymer Particles-A Step Forward for Chromatography
    • Ugelstad, J., Söderberg, L., Berge, A. and Bergström, J., "Monodisperse Polymer Particles-A Step Forward for Chromatography," Nature, 303, 95 (1983).
    • (1983) Nature , vol.303 , pp. 95
    • Ugelstad, J.1    Söderberg, L.2    Berge, A.3    Bergström, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.