Determination of the optimum pH for isolatsion of a compound with multiple pKa's from aqueous-organic solvent mixtures

Organic Process Research and Development

Volumn 5, Issue 1, 2001, Pages 77-79

  Crocker, Louis S ^a   Wang, Yaling ^a   McCauley, James A ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035587016     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op000283f     Document Type: Article

References (8)

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2. Bates, R. G. Determination of pH; John Wiley & Sons Inc.: New York, 1964.
3. Hammett, L. P. J. Am. Chem. Soc. 1928, 50, 2666.
4. (a) Britton, H. T. S. Hydrogen Ions; D. Van Nostrand Co., Inc.: New York, 1956.
5. (b) Noyes, A. A. Z. Phys. Chem. 1893, 11, 495.
6. Mukerjee, P.; Ostrow, J. D. Tetrahedron Lett. 1998, 39, 423.
7. Vesala, A.; Saloma, E. Acta Chem. Scand, 1976, A30, 277.
8. Herr, R. J.; Meckler, H.; Scuderi, F., Jr. Org. Process Res. Dev. 2000, 4, 43.