Characterisation of taurine uptake in human KB MDR and non-MDR tumour cell lines in culture

Anticancer Research

Volumn 21, Issue 5, 2001, Pages 3397-3406

  Wersinger, Christophe ^a   Rebel, Gerard ^a   Lelong Rebel, Isabelle Hanna ^a  

^a IRCAD   (France)

Author keywords

Chemotherapeutic agents; KB cell lines; MDR cells; Taurine uptake; Verapamil

Indexed keywords

4 (2 HYDROXYETHYL) 1 PIPERAZINEETHANESULFONIC ACID; ANTIINFECTIVE AGENT; BETA AMINO ACID; BUFFER; CHLORIDE ION; DOXORUBICIN; SODIUM ION; TAURINE; TAURINE DERIVATIVE; VERAPAMIL; VINBLASTINE;

AMINO ACID TRANSPORT; ARTICLE; BINDING AFFINITY; CELL PROLIFERATION; CELL TYPE; CHLORIDE TRANSPORT; CONTROLLED STUDY; DIFFUSION; DRUG SELECTIVITY; HUMAN; HUMAN CELL; HYPEROSMOLARITY; MULTIDRUG RESISTANCE; OSMOSIS; PRIORITY JOURNAL; SODIUM TRANSPORT; TUMOR CELL CULTURE;

BUFFERS; CELL DIVISION; DOXORUBICIN; DRUG INTERACTIONS; DRUG RESISTANCE, MULTIPLE; HUMANS; KB CELLS; KINETICS; TAURINE; VERAPAMIL; VINBLASTINE;

EID: 0035569938     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Physiological actions of taurine
2. Taurine: Its biological role and clinical implications
3. Taurine: Biological update
4. Taurine in development
5. Taurine in the central nervous system and the mammalian actions of taurine
6. Reduction of doxorubicin-induced cardiotoxicity in mice with taurine
7. Protective effect of taurine against doxorubicin-induced cardiotoxicity in perfused chick hearts
8. Protection by taurine against adriamycin-induced proteinuria and hyperlipidemia in rats
9. Detailed study of the different taurine uptake systems of colon LoVo MDR and non-MDR cell lines
10. Taurine analogue modulation of taurine uptake by two different mechanisms in cultured glial cells
11. Biochemistry of the multidrug resistance mediated by the multidrug transporter
12. The biology of the P-Glycoprotein
13. Isolation and genetic characterisation of human KB cell lines resistant to multiple drugs
14. Quantification of cells cultured on 96-well plates
15. pH drift of "physiological buffers" and culture media used for cell incubation during in vitro studies
16. Effect of HEPES on the taurine uptake by cultured glial cells
17. 2
18. Protein measurement with the Folin phenol reagent
19. DNA fluorimetric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water
20. Neuronal cells mature faster on polyethyleneimine coated plates than on polylysine coated plates
21. Multiple drug resistant human KB carcinoma cells independently selected for high resistance to colchicine, adriamycin or vinblastine show changes in expression of specific proteins
22. Expression and regulation of the taurine transporter in cultured cell lines of human origin
23. Polarity of taurine transport in cultured renal epithelial cell lines LLC-PKI and MDCK
24. Regression of high affinity carrier-mediated intestinal transport of taurine in adult cats
25. + dependent carrier on the plasma membrane
26. Taurine transport across hepatocyte plasma membranes: Analysis in isolated rat liver sinusoidal plasma membrane vesicles
27. Taurine transport by microvillous membrane vesicles and the perfused cotyledon of the human placenta
28. + dependent transport of taurine by membrane vesicles of neuroblastoma x glioma hybrid cells
29. - dependent uptake of taurine and β-alanine by cultured glial cells. Modulation by composition and osmolarity of medium
30. Taurine and β-alanine transport in an established human kidney cell line derived from the proximal tubule
31. + independent taurine influx in flounder erythrocytes and its association with the volume regulatory taurine efflux
32. On the role of glial cells in mammalian nervous system. Uptake, excretion and metabolism of putative neurotransmitters by cultured glial tumour cells
33. High affinity transport of taurine and β-alanine and low affinity transport of γ-aminobutyric acid by a single transport system in cultured glioma cells
34. Characterisation of taurine transport in human glioma GL15 cell line: Regulation by protein kinase C
35. Characterisation of taurine uptake by neuronal and glial cells in culture
36. Taurine, hypotaurine and GABA uptake by cultured neuroblastoma cells
37. + dependent uptake and release of taurine by neuroblastoma x glioma hybrid cells
38. Taurine transport in Ehrlich Ascites tumour cells, specificity and chloride dependence
39. Transport of taurine and its regulation by protein kinase C in the JAR human placental choriocarcinoma cell line
40. Functional characterisation and chromosomal localisation of a cloned taurine transporter from human placenta
41. Characterisation and regulation of taurine transport in Caco-2 human intestinal cells
42. Constitutive expression of the taurine transporter in a human colon carcinoma cell line
43. Physiological and experimental regulation of taurine content in the heart
44. Taurine transport in skate hepatocytes. Uptake and efflux
45. Taurine and cell volume maintenance in the shark rectal gland: Cellular fluxes and kinetics
46. The taurine content of avian erythrocytes and its role in osmoregulation
47. Characterisation of a carrier-mediated transport system for taurine in the fetal mouse heart in vitro
48. β-amino acid transport across the renal brush-border membrane is coupled to both Na and Cl
49. Pharmacology of drugs that alter multidrug resistance in cancer
50. Molecular targets in oncology: Implications of the multidrug resistance gene
51. Reversal of multidrug resistance to cancer chemotherapy
52. Certain calcium channel blockers bind specifically to multidrug resistant KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein
53. Fluorescent verapamil derivative for monitoring activity of the multidrug transporter
54. Transport and metabolism of polyamines in wild and multidrug resistant human leukemia (K562) cells
55. Partial purification of the human multidrug resistance pump: Characterization of the drug-stimulatable ATP hydrolysis
56. Epidermal growth factor receptor is increased in multidrug resistant chinese hamster and mouse tumor cells
57. High field proton NMR investigations of the metabolic profiles of multidrug-sensitive and resistant leukaemic cell lines: Evidence for diminished taurine levels in multidrug-resistant cells
58. 2-Deoxy-D-glucose toxicity and transport in human multidrug-resistant KB carcinoma cell lines
59. Membrane composition and multidrug resistance
60. A comparison of membrane properties and composition between cell lines selected and transfected for multidrug resistance