Differential Roles of Endogenous Nitric Oxide on Neural Regulation of Basal Exocrine Pancreatic Secretion in Intact and Denervated Pancreas

Pancreatology

Volumn 1, Issue 2, 2001, Pages 96-101

  Zoucas, Evita ^a   Nilsson, Carina ^a   Ihse, Ingemar ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Endogenous nitric oxide; Exocrine pancreatic secretion; Pancreas denervation

Indexed keywords

AMYLASE; ARGININE; N(G) NITROARGININE; NITRIC OXIDE; PROTEIN;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DENERVATION; DRUG EFFECT; HOMEOSTASIS; INNERVATION; MALE; ORGAN SIZE; PANCREAS; PHYSIOLOGY; RAT; REFERENCE VALUE; SECRETION; SPRAGUE DAWLEY RAT; VASCULARIZATION;

AMYLASES; ANIMALS; ARGININE; DENERVATION; HOMEOSTASIS; MALE; NITRIC OXIDE; NITROARGININE; ORGAN SIZE; PANCREAS; PROTEINS; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES;

EID: 0035554416     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1159/000055800     Document Type: Article

References (27)

1. Holst JJ: Neural regulation of pancreatic exocrine function; in Go VLM, DiMagno EP, Gardner JD, Lebenthal E, Reber HA, Scheele GA (eds): The Pancreas: Biology, Pathobiology and Disease. New York, Raven Press, 1993, pp 381-402.
2. Li P, Chang M, Chey YY: Neuronal regulation of the release and action of secretin-releasing peptide and secretin. Am J Physiol 1995;269: G305-G312.
3. Glasbrenner B, Dominguez-Munoz E, Riepl RL, Vetsi A, Malfertheiner P: Cholecystokinin and pancreatic polypeptide release in diabetic patients with and without autonomic neuropathy. Dig Dis Sci 1995;40:406-411.
4. Ekblad E, Alm P, Sundler F: Distribution, origin and projections of nitric oxide synthase-containing neurones in gut and pancreas. Neuroscience 1994;63:233-248.
5. Konturek JW, Hengst K, Kulesza E, Gabryelewicz, Konturek SJ, Domschke W: Role of endogenous nitric oxide in the control of exocrine and endocrine pancreatic secretion in humans. Gut 1997;40:86-91.
6. Patel AG, Toyama MT, Nguyen TN, Cohen GA, Ignarro LI, Reber HA, Ashley SW: Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats. Gastroenterology 1995;108:1215-1220.
7. Wrenn RW, Currie MG, Herman LE: Nitric oxide participates in the regulation of pancreatic acinar cell secretion. Life Sci 1994;55:511-518.
8. Ceccateli S, Lundberg JM, Zhang X, Aman K, Hökfelt T: Immunohistochemical demonstration of nitric oxide synthase in the peripheral autonomic nervous system. Brain Res 1994; 656:381-395.
9. Kirchgessner AL, Liu MT, Gershon MD: NADPH diaphorase (nitric oxide synthase)-containing nerves in the enteropancreatic innervation: Sources, co-stored neuropeptides and pancreatic function. J Comp Neurol 1994; 342:115-130.
10. Greenberg SS, Diecke FPJ, Cantor E, Peevy K, Tanaka TP: Inhibition of sympathetic neurotransmitter release by modulators of cGMP in canine vascular smooth muscle. Eur J Pharmacol 1990;187:409-423.
11. Wiklund CU, Olgart C, Wiklund NP, Gustafsson LE: Modulation of cholinergic and substance P-like neurotransmission by nitric oxide in the guinea-pig ileum. Br J Pharmacol 1993; 110:833-839.
12. Zoucas E, Nilsson C, Alm P, Ihse I: Selective microsurgical sympathetic denervation of the rat pancreas. Eur Surg Res 1996;28:349-352.
13. Dahm P, Thörne J, Zoucas E, Mårtensson L, Myhre E, Blomquist S: Differential effects of nitric oxide synthase modulation on porcine systemic and pulmonary circulation in vivo. Crit Care Med 1997;25:280-285.
14. Eggstein M, Kreutz FH: Vergleichende Untersuchungen zur quantitativen Eiweissbestimmung in Liquor und eiweissigen Lösungen. Klin Wochenschr 1955;37/38:879-884.
15. Maouyo D, Morisset J: Amazing pancreas: Specific regulation of pancreatic secretion of individual digestive enzymes in rats. Am J Physiol 1995, 268:E349-E359.
16. Shetzline M, Liddl R: Neurohumoral control of the exocrine pancreas. Gastroenterology 1966; 12:423-428.
17. Holst JJ, Rasmussen TN, Schmidt P: Role of nitric oxide in neurally induced pancreatic exocrine secretion in pigs. Am J Physiol 1994;266: 206-213.
18. Umehara K, Kataoka K, Ogura T, Esumi H, Kashima K, Ibata Y, Okamura H: Comparative distribution of nitric oxide synthase in pancreas of the dog and rat: Immunocytochemistry of neuronal type NOS and histochemistry of NADPH-diaphorase. Brain Res Bull 1996; 42:469-478.
19. Polloch JS, Nakane M, Buttery LDK, Martinez A, Springall D, Polak JM, Fostermann U, Murad F: Characterisation and localisation of endothelial nitric oxide synthase using specific monoclonal antibodies. Am J Physiol 1993; 265:C1379-C1387.
20. Rand M. Li C: Nitric oxide as neurotransmitter in peripheral nerves: Nature of neurotransmission and mechanisms of transmission. Annu Rev Physiol 1995;57:659-662.
21. Bilski J, Konturek JW, Konturek SJ, Domschke W: The involvement of endogenous nitric oxide in vagal-cholinergic stimulation of exocrine and endocrine pancreas in dogs. Int J Pancreatol 1995;18:41-49.
22. Konturek SJ, Szlacheic A, Dembinski A, Warzecha Z, Jaworek J, Stachura J: Nitric oxide in pancreatic secretion and hormone-induced pancreatitis in rats. Int J Pancreatol 1994;15: 19-28.
23. Konturek SJ, Bilski J, Konturek PK, Cieszkowski M, Pawlik W: Role of endogenous nitric oxide in the control of canine pancreatic secretion and blood flow. Gastroenterology 1993; 104:896-902.
24. Lohinai Z, Balla I, Marezis T, Vass L, Kovach AG: The effect of a nitric oxide donor and an inhibitor of nitric oxide synthase on blood flow and vascular resistance in feline submandibular, parotid and pancreatic glands. Arch Oval Biol 1996;41:699-704.
25. Yamamoto R, Wada A, Asada Y, Niina H, Sumiyoshi A: N omega-nitro-L-arginine, an inhibitor of nitric oxide synthesis, decreases noradrenaline outflow in rat isolated perfused mesenteric vasculature. Naunyn Schmiedebergs Arch Pharmacol 1993;347:238-240.
26. Nilsson C, Zoucas E, Sternby B, Ihse I: The effect of selective sympathetic denervation on pancreatic exocrine secretion. Res Exp Med 1996;197:147-155.
27. Maczka M, Thor P, Bilski J, Konturek SJ: Nitric oxide and the interrelation between intestinal motility and pancreatic secretion in fasted and fed dogs. J Physiol Pharmacol 1994;45: 285-298.