Hexamethyldisiloxane: A 13-week subchronic whole-body vapor inhalation toxicity study in Fischer 344 rats

International Journal of Toxicology

Volumn 20, Issue 6, 2001, Pages 391-399

  Cassidy, Simon L ^a   Kolesar, Gary B ^a   Dochterman, L Wayne ^a   Meeks, Robert G ^a   Dotti, Antonio ^b   Chevalier, H J ^b  

^a DOW CORNING CORPORATION   (United States)

^b Research and Consulting Company Ltd   (Switzerland)

Author keywords

Hexamethyldisiloxane; HMDS; Inhalation; Kidney histology; Rat; Subchronic

Indexed keywords

ALPHA 2 GLOBULIN; HEXAMETHYLDISILOXANE; SILOXANE; UNCLASSIFIED DRUG; CREATININE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHRONIC TOXICITY; CONTROLLED STUDY; FEMALE; FOOD INTAKE; HISTOPATHOLOGY; MALE; MORTALITY; NEPHROTOXICITY; NONHUMAN; RAT; TOXICITY TESTING; URINE LEVEL; WEIGHT GAIN; ANIMAL; BLOOD; DOSE RESPONSE; DRUG EFFECT; FISCHER 344 RAT; INHALATIONAL DRUG ADMINISTRATION; KIDNEY; ORGAN SIZE; PATHOLOGY; SEX DIFFERENCE; URINALYSIS; VOLATILIZATION;

ANIMALIA;

ADMINISTRATION, INHALATION; ANIMALS; CREATININE; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; KIDNEY; MALE; ORGAN SIZE; RATS; RATS, INBRED F344; SEX FACTORS; SILOXANES; TOXICITY TESTS; UREA; URINALYSIS; VOLATILIZATION;

EID: 0035544062     PISSN: 10915818     EISSN: None     Source Type: Journal    
DOI: 10.1080/109158101753333677     Document Type: Article

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