Hb Gerland [α55(E4)Val → Ala (α2)]: A new neutral α chain variant involving the α2 gene

Hemoglobin

Volumn 25, Issue 4, 2001, Pages 417-420

  Lacan, Philippe ^a   Aubry, Martine ^a   Couprie, Nicole ^b   Francina, Alain ^a  

^a EDOUARD HERRIOT HOSPITAL   (France)

^b LMM Laboratoire Marcel Merieux   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN ALPHA CHAIN; HEMOGLOBIN GERLAND; HEMOGLOBIN VARIANT; UNCLASSIFIED DRUG; GLOBIN;

ADULT; ARTICLE; CASE REPORT; CHILD; DNA SEQUENCE; FAMILY STUDY; FEMALE; GENE MUTATION; HEMOGLOBIN ANALYSIS; HEMOGLOBINOPATHY; HUMAN; MALE; MICROCYTIC ANEMIA; POLYMERASE CHAIN REACTION; PROTEIN STABILITY; RESTRICTION MAPPING; ALPHA THALASSEMIA; AMINO ACID SUBSTITUTION; ANEMIA; ERYTHROCYTE DISORDER; ETHNOLOGY; FAMILY HEALTH; FRANCE; GENETIC VARIABILITY; GENETICS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NUCLEOTIDE SEQUENCE; PATHOLOGY; POINT MUTATION;

ADULT; ALPHA-THALASSEMIA; AMINO ACID SUBSTITUTION; ANEMIA; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA MUTATIONAL ANALYSIS; ERYTHROCYTES, ABNORMAL; FAMILY HEALTH; FRANCE; GLOBINS; HEMOGLOBINS, ABNORMAL; HUMANS; MALE; POINT MUTATION; POLYMERASE CHAIN REACTION; VARIATION (GENETICS);

EID: 0035543929     PISSN: 03630269     EISSN: None     Source Type: Journal    
DOI: 10.1081/HEM-100107879     Document Type: Article

References (9)

1. Hemoglobin debrousse [β96(FG3)Leu → Pro]: A new unstable hemoglobin with twofold increased oxygen affinity
2. A new α chain variant Hb sallanches [α2 104(G11)Cys → Tyr] associated with Hb H disease in one homozygous patient
3. Rapid HPLC techniques for globin chain synthesis studies
4. Detection of globin chains by reversed-phase high-performance liquid chromatography
5. A simple method for the detection of unstable haemoglobins
6. Locus assignment of human α globin mutations by selective amplification and direct sequencing
7. anti 3.7 triplication by enzymatic amplification analysis
8. Detection of α-globin gene disorders by a simple PCR methodology
9. Hb Roubaix [α(55(E4)Val → Leu]: A new neutral hemoglobin variant involving the α] gene