Comparative metabolism of [14C]benzene to excretable products and bioactivation to DNA-binding derivatives in maternal and neonatal mice

Archives of Toxicology

Volumn 75, Issue 10, 2001, Pages 574-582

  Iba, Michael M ^a   Ghosal, Anima ^a   Snyder, Robert ^a  

^a RUTGERS UNIVERSITY   (United States)

Author keywords

Benzene; Bioactivation; DNA adducts; Metabolites; Mothers; Suckling mice

Indexed keywords

BENZENE; BENZENE DERIVATIVE; CARBON 14; DNA; MUCONIC ACID; PHENOL; PHENYL GLUCURONIDE; UNCLASSIFIED DRUG; CARBON; DIAGNOSTIC AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONJUGATE; CONTROLLED STUDY; COVALENT BOND; DNA BINDING; EXCRETION; FEMALE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LACTATION; LIVER LEVEL; METABOLIC ACTIVATION; METABOLISM; METABOLITE; MOTHER; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; SUCKLING; TOXICITY TESTING; URINALYSIS; URINE LEVEL; ANIMAL; BIOTRANSFORMATION; COMPARATIVE STUDY; LIVER; MALE; PREGNANCY; URINE;

ANIMALIA;

ANIMALS; ANIMALS, SUCKLING; BENZENE; BIOTRANSFORMATION; CARBON RADIOISOTOPES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DNA; FEMALE; LIVER; MALE; MICE; PREGNANCY;

EID: 0035543685     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-001-0290-x     Document Type: Article

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