Tris(2,4,6-trimethoxyphenyl)phosphine (TTMPP): A novel catalyst for selective deacetylation

Chemistry Letters

Volumn , Issue 9, 2001, Pages 934-935

  Yoshimoto, Kazuya ^a   Kawabata, Hirotoshi ^a   Nakamichi, Natsuki ^a   Hayashi, Masahiko ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035540089     PISSN: 03667022     EISSN: None     Source Type: Journal    
DOI: 10.1246/cl.2001.934     Document Type: Article

References (6)

1. T. W. Greene and P. G. M. Wuts, "Protective Groups in Organic Synthesis," 3rd ed., John Wiley & Sons, New York (1999), pp 150-160 and references cited therein.
2. M. Wada and S. Higashizaki, J. Chem. Soc., Chem. Commun., 1984, 482.
3. S. Matsukawa, N. Okano, and T. Imamoto, Tetrahedron Lett., 41, 103 (2000).
4. The use of methanol was essential for deacetylation using TTMPP system. That is, the deacetylation reaction in ethanol or isopropyl alcohol did not take place.
5. The reactions of 1 with 10 mol% of tris(2,6-dimethoxyphenyl)phosphine even at 80 °C for 24 h afforded 3 only in 8% yield. Starting material 1 was recovered in 65% yield.
6. 1H NMR analysis.