An improved procedure for the reduction of 2,4-dinitrobenzaldehyde to 2,4-diaminobenzaldehyde with iron and acetic acid under dose-controlled conditions

Organic Process Research and Development

Volumn 5, Issue 5, 2001, Pages 539-541

  Whritenour, David C ^a   Brenek, Steven J ^a   Tom, Norma J ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0035537554     PISSN: 10836160     EISSN: None     Source Type: Journal    
DOI: 10.1021/op0100089     Document Type: Article

References (4)

1. Merlic, Craig A.; Motamed, Soheil; Quinn, Bruce J. Org. Chem. 1995, 60, 3365-3369.
2. DSC Result of isolated solid: Exothermic decomposition near 218 °C liberating 2669 J/g of energy. DSC Result of 1:1 w/w in ethyl acetate: Exothermic decomposition near 219 °C liberating 477 J/g of energy.
3. BAM Fallhammer Test: Impact sensitive above 56 J.
4. Owsley, D. C.; Bloomfield, J. J. Synthesis 1977, 118-120.