Methods determining phosphor imaging limits of quantitation in whole-body autoradiography rodent tissue distribution studies affect predictions of 14C human dosimetry

Journal of Pharmacological and Toxicological Methods

Volumn 46, Issue 2, 2001, Pages 83-91

  Solon, Eric G ^a   Lee, Frank ^a  

^a Quest Pharmaceutical Services   (United States)

Author keywords

ADME; Human radioactivity dosimetry; Limits of quantitation; Pharmacokinetics; Phosphor imaging; Radioluminography; Rat; Tissue distribution; Whole body autoradiography

Indexed keywords

CARBON 14; PHOSPHORUS; TRITIUM; CARBON;

ANIMAL TISSUE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DOSIMETRY; DRUG HALF LIFE; MALE; NONHUMAN; PREDICTION; QUANTITATIVE ANALYSIS; RADIATION EXPOSURE; RADIATION MEASUREMENT; RADIOACTIVITY; RAT; RODENT; TECHNIQUE; TISSUE DISTRIBUTION; WHOLE BODY AUTORADIOGRAPHY; ANIMAL; AUTORADIOGRAPHY; COMPARATIVE STUDY; FORECASTING; HUMAN; METHODOLOGY; PHYSIOLOGY; RADIOMETRY; SPRAGUE DAWLEY RAT; WHOLE BODY COUNTING;

ANIMAL; AUTORADIOGRAPHY; CARBON RADIOISOTOPES; COMPARATIVE STUDY; FORECASTING; HUMAN; MALE; RADIOMETRY; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION; WHOLE-BODY COUNTING; ANIMALS; HUMANS;

RODENTIA; TRIXIS;

EID: 0035527671     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(02)00162-4     Document Type: Article

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