The use of on-line and off-line chromatographic extraction techniques coupled with mass spectrometry for support of in vivo and in vitro assays in drug discovery.

Current topics in medicinal chemistry

Volumn 1, Issue 5, 2001, Pages 463-471

  Masucci, J J ^a   Caldwell, G G ^a   Jones, W W ^a   Juzwin, S S ^a   Sasso, P P ^a   Evangelisto, M ^a  

^a R W JOHNSON PHARMACEUTICAL RES I   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANTIHYPERTENSIVE AGENT; ANTIULCER AGENT; CIMETIDINE; DRUG; HISTAMINE H1 RECEPTOR ANTAGONIST; HYDROCHLOROTHIAZIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PHOSPHODIESTERASE INHIBITOR; PROMETHAZINE; THEOPHYLLINE;

ARTICLE; CELL STRAIN CACO 2; DRUG SCREENING; HUMAN; INSTRUMENTATION; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; METHODOLOGY;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTI-ULCER AGENTS; ANTIHYPERTENSIVE AGENTS; ASPIRIN; CACO-2 CELLS; CHROMATOGRAPHY, LIQUID; CIMETIDINE; DRUG EVALUATION, PRECLINICAL; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HISTAMINE H1 ANTAGONISTS; HUMANS; HYDROCHLOROTHIAZIDE; PHARMACEUTICAL PREPARATIONS; PHOSPHODIESTERASE INHIBITORS; PROMETHAZINE; THEOPHYLLINE;

EID: 0035523196     PISSN: 15680266     EISSN: None     Source Type: Journal    
DOI: 10.2174/1568026013394985     Document Type: Article

References (0)