An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)

British journal of clinical pharmacology

Volumn 52, Issue 5, 2001, Pages 555-561

  Palmer, J L ^a   Scott, R J ^a   Gibson, A ^a   Dickins, M ^a   Pleasance, S ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CAFFEINE; CENTRAL MUSCLE RELAXANT; CHLORZOXAZONE; CYTOCHROME P450; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; DEBRISOQUINE; DICLOFENAC; MEPHENYTOIN; MIDAZOLAM; N DEMETHYLASE; UNSPECIFIC MONOOXYGENASE;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLOOD; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG INTERACTION; FEMALE; HUMAN; MALE; METABOLISM; ORAL DRUG ADMINISTRATION; RANDOMIZED CONTROLLED TRIAL;

ADMINISTRATION, ORAL; ADULT; AREA UNDER CURVE; ARYL HYDROCARBON HYDROXYLASES; CAFFEINE; CHLORZOXAZONE; CROSS-OVER STUDIES; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; DEBRISOQUIN; DICLOFENAC; DRUG INTERACTIONS; FEMALE; HUMANS; MALE; MEPHENYTOIN; MIDAZOLAM; MUSCLE RELAXANTS, CENTRAL; OXIDOREDUCTASES, N-DEMETHYLATING;

EID: 0035514875     PISSN: 03065251     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0306-5251.2001.01479.x     Document Type: Article

References (0)