Determination of plasma free carnitine by electrospray tandem mass spectrometry

Annals of Clinical Biochemistry

Volumn 38, Issue 6, 2001, Pages 665-670

  Hardy, David T ^a,b   Preece, Mary Anne ^b   Green, Anne ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BIRMINGHAM CHILDREN S HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CARNITINE;

ARTICLE; BLOOD; BLOOD ANALYSIS; COMPARATIVE STUDY; HUMAN; MASS SPECTROMETRY; METHODOLOGY;

BLOOD CHEMICAL ANALYSIS; CARNITINE; COMPARATIVE STUDY; HUMAN; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SUPPORT, NON-U.S. GOV'T;

EID: 0035512058     PISSN: 00045632     EISSN: None     Source Type: Journal    
DOI: 10.1258/0004563011901073     Document Type: Article

References (10)

1. De Sousa CA, English NR, Stacey TE, Chalmers RA. Measurement of L-carnitine and acylcarnitines in body fluids and tissue in children and adults. Clin Chim Acta 1990; 187: 317-28
2. Roe DS, Terada N, Millington DS. Automated analysis for free and short-chain acylcarnitine in plasma with a centrifugal analyzer. Clin Chem 1992; 38: 2215-20
3. Rashed MS, Ozand PT, Bucknall MP, Little D. Diagnosis of inborn errors of metabolism from blood spots by acylcarnitine and amino acid profiling using automated electrospray tandem mass spectrometry. Pediatr Res 1995; 38: 324-34
4. Vianey-Saban C, Guffon N, Delolne F, Guibaud P, Mathieu M, Divry P. Diagnosis of inborn errors of metabolism by acylcarnitine profiling in blood using tandem mass spectrometry. J Inher Metab Dis 1997; 20: 411-4
5. Delolme F, Vianey-Saban C, Guffon N, Faure Bonvin J, Guibaud P, Becchi M, et al. Study of plasma acylcarnitines using tandem mass spectrometry. Application to the diagnosis of metabolic hereditary disease. Arch Pediatr 1997; 4: 819-26
6. Millington DS, Terada N, Chace DH, Chen YT, Ding JH, Kodo N, et al. The role of tandem mass spectrometry in the diagnosis of fatty acid oxidation defects. Prog Clin Biol Res 1992; 375: 339-54
7. Millington DS, Kodo N, Norwood DL, Roe CR. Tandem mass spectrometry: A new method for acylcarnitine profiling with potential for neonatal screening for inborn errors of metabolism. J Inher Metab Dis 1990; 13: 321-4
8. Millington DS, Norwood DL, Kodo N, Roe CR, Inoue F. Application of fast atom bombardment with tandem mass spectrometry and liquid chromatography-mass spectrometry to the analysis of acylcarnitine in human urine, blood and tissue. Anal Biochem 1989; 180: 331-9
9. Johnson DW. Inaccurate measurement of free carnitine by the electrospray tandem mass spectrometry screening method for blood spots. J Inher Metab Dis 1999; 22: 201-2
10. Stevens RD, Hillman SL, Worthy S, Sanders D, Millington DS. Assay for free and total carnitine in human plasma using tandem mass spectrometry. Clin Chem 2000; 46: 727-9