Enhancing performance of three-phase catalytic packed-bed reactors

AIChE Journal

Volumn 47, Issue 11, 2001, Pages 2548-2556

  Wilhite, B A ^a   Wu, R ^a,b   Huang, X ^a   McCready, M J ^a   Varma, A ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ALUMINA; BENZENE; CATALYSIS; CHEMICAL REACTORS; HYDROGENATION; STYRENE;

PACKED-BED REACTORS;

PACKED BEDS;

ACETYLENE DERIVATIVE; ALUMINUM OXIDE; DECANE; ETHYLBENZENE; PHENYLACETYLENE; PLATINUM; STYRENE; TETRADECANE; UNCLASSIFIED DRUG;

HYDROGENATION; PACKED BED; PERFORMANCE PREDICTION; PULSATING FLOW; REACTION; REACTOR;

ARTICLE; CALCULATION; CATALYSIS; CATALYST; CHEMICAL PROCEDURES; CHEMICAL REACTION; EXPERIMENTAL TEST; FLOW; HYDROGENATION; PACKED BED REACTOR; PERFORMANCE; PREDICTION; QUALITATIVE ANALYSIS; THEORY;

EID: 0035510067     PISSN: 00011541     EISSN: None     Source Type: Journal    
DOI: 10.1002/aic.690471117     Document Type: Article

References (22)

1. Al-Dahhan, M. H., and M. P. Dudukovic. "Catalyst Wetting Efficiency in Trickle-Bed Reactors at High Pressure," Chem. Eng. Sci., 50, 2377 (1995).
2. Aramendia, M. A., V. Borau, C. Jimenez, J. M. Marinas, M. E. Sempere, and F. J. Urbano, "Optimization of the Selective Semi-Hydrogenation of Phenylacetylene with Supported Palladium Systems," Appl Catal., 63, 375 (1990).
3. Arena, F., G. Cum, R. Gallo, and A. Parmaliana, "Palladium Catalysts Supported on Oligomeric Aramides in the Liquid-Phase Hydrogenation of Phenylacetylene," J. Mol. Catal., A: Chemical, 110, 235 (1998).
4. Blok, J. R. and A. A. H. Drinkenburg, "Hydrodynamics and Mass Transfer in Pulsing Trickle-Bed Columns," ACS Symp. Ser., 196, 393 (1982).
5. Chou, T. S., F. L. Worley, and D. Luss, "Local Particle-Liquid Mass Transfer Fluctuations in Mixed-Phase Cocurrent Downflow through a Fixed Bed in the Pulsing Regime," Ind. Eng. Chem. Fundam., 18, 279 (1979).
6. Duca, D., L. F. Liotta, and G. Deganello, "Liquid Phase Hydrogenation of Phenylacetylene on Pumice Supported Palladium Catalysts," Catal. Today, 24, 15 (1995).
7. Dudukovic, M. P., F. Larachi, and P. L. Mills, "Multiphase Reactors-Revisited," Chem. Eng. Sci., 54, 1975 (1999).
8. Jiang, Y., M. R. Khadilkar, M. H. Al-Dahhan, and M. P. Dudukovic, "Two-Phase Flow Distribution in 2-D Trickle-Bed Reactors," Chem. Eng. Sci., 54, 2409 (1999).
9. Kawakami, K., and K. Kusonoki, "The Effects of Intraparticle Diffusion on the Yield of the Liquid-Phase. Hydrogenation of Phenylacetylene in a Stirred Basket Reactor," J. Chem. Eng. Japan, 9, 469 (1976).
10. Krieg, D. A., J. A. Helwick, P. O. Dillon and M. J. McCready, "Origin of Disturbances in Cocurrent Gas-Liquid Packed Bed Flows," AIChE J., 41, 1653 (1995).
11. Maurer, B. R., and M. Galobardes, "Selective Hydrogenation of Phenylacetylene in the Presence of Styrene," The Dow Chemical Company, Midland, MI., U.S. Patent No. 4,822,936 (1989).
12. Mills, P. L., P. A. Ramachandran, and R. V. Chaudhari, "Multiphase Reaction Engineering for Fine Chemicals and Pharmaceuticals," Rev. Chem. Eng., 8, 1 (1992).
13. Mochizuki, S., and T. Matsui, "Selective Hydrogenation and Mass Transfer in a Fixed-Bed Catalytic Reactor with Gas-Liquid Concurrent Upflow," AIChE J., 22, 904 (1976).
14. Ng, K. M., and C. F. Chu, "Trickle-Bed Reactors," Chem. Eng. Prog., 47, 55 (1987).
15. Priddy, D. B. and J. M. Roe, "Hydrogenation of Phenylacetylene Prior to Styrene Polymerization, The Dow Chemical Company, Midland, MI, U. S. No. Patent 4,389,517, (1983).
16. Rao, V. G., and A. A. H. Drinkenburg, "Solid-Liquid Mass Transfer in Packed Bed with Cocurrent Gas-Liquid Downflow," AIChE J., 31, 1059 (1985).
17. Sims, W. B., S. W. Gaskey, and D. Luss, "Effect of Flow Regime and Liquid Velocity on Conversion in a Trickle-Bed Reactor," Ind. Eng. Chem. Res., 33, 2530 (1994).
18. Varma, A., and M. Morbidelli, Mathematical Methods in Chemical Engineering, Chap. 8, Oxford University Press, New York (1997).
19. Visser, J. B. M., A. Stankiewicz, L. L. van Dierendonck, L. Manna, S. Sicardi, and G. Baldi, "Dynamic Operation of a Three-Phase Upflow Reactor for the Hydrogenation of Phenylacetylene," Catal. Today, 20, 485 (1994).
20. Watson, P. C. and M. P. Harold, "Rate Enhancement and Multiplicity in a Partially Wetted and Filled Pellet: Experimental Study," AIChE J., 40, 97 (1994).
21. Wu, R., M. J. McCready, and A. Varma, "Influence of Mass Transfer Coefficient Fluctuation Frequency on Performance of Three-Phase Packed-Bed Reactors," Chem. Eng. Sci., 50, 3333 (1995).
22. Wu, R., M. J. McCready, and A. Varma, "Effect of Pulsing on Reaction Outcome in a Gas-Liquid Catalytic Packed-Bed Reactor," Catal. Today, 48, 195 (1999).