A nuclear modifier for a mitochondrial DNA disorder

Trends in Genetics

Volumn 17, Issue 11, 2001, Pages 609-611

  Taanman, Jan Willem ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOGLYCOSIDE; ANTIBIOTIC AGENT; MITOCHONDRIAL DNA;

ANIMAL MODEL; DNA MODIFICATION; ENERGY; GENE LOCUS; GENE MUTATION; GENETIC CODE; HEARING LOSS; INNER EAR; MOUSE; NONHUMAN; OTOTOXICITY; PHENOTYPE; PRIORITY JOURNAL; RNA GENE; SHORT SURVEY; TISSUE SPECIFICITY;

ANIMALIA;

EID: 0035500274     PISSN: 01689525     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-9525(01)02441-6     Document Type: Review

References (21)

1. Mitochondrial genetics and disease
2. Mitomap: A human mitochondrial genome database - 1998 Update
3. Mitochondrial ribosomal RNA mutation associated with both antibiotic-induced and non-syndromic deafness
4. Evidence for complex nuclear inheritance in a pedigree with nonsyndromic deafness due to a homoplasmic mitochondrial mutation
5. Familial progressive sensorineural deafness is mainly due to the mtDNA A1555G mutation and is enhanced by treatment with aminoglycosides
6. Mitochondrial deafness mutations reviewed
7. Prevalence of mitochondrial gene mutations among hearing impaired patients
8. Candidate locus for a nuclear modifier gene for maternally inherited deafness
9. A molecular basis for human hypersensitivity to aminoglycoside antibiotics
10. Interaction of antibiotics with functional sites in 16S ribosomal RNA
11. Cross-linking of streptomycin to the 16S ribosomal RNA of Escherichia coli
12. The aminoglycosides
13. Specific binding of aminoglycosides to a human rRNA construct based on a DNA polymorphism which causes aminoglycoside-induced deafness
14. Biochemical evidence for nuclear gene involvement in phenotype of non-syndromic deafness associated with mitochondrial 12S rRNA mutation
15. A biochemical basis for the inherited susceptibility to aminoglycoside ototoxicity
16. Nuclear background determines biochemical phenotype in the deafness-associated mitochondrial 12S rRNA mutation
17. The mitochondrial genome: Structure, transcription, translation and replication
18. Mammalian mitochondrial ribosomal proteins (4). Amino acid sequencing, characterization, and identification of corresponding gene sequences
19. A nuclear-mitochondrial DNA interaction affecting hearing impairment in mice
20. Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice
21. 2+-ATPase gene cause deafness in deafwaddler mice