Insulin secretion and sensitivity during oral glucose tolerance test in Korean lean elderly women

Journal of Korean Medical Science

Volumn 16, Issue 5, 2001, Pages 592-597

  Kim, Jaetaek ^a   Choi, Seungjin ^a   Kong, Beongho ^a   Oh, Yeonsahng ^a,b   Shinn, Soonhyun ^a  

^a Chung Ang University College of Medicine   (South Korea)

^b Chung Ang University   (South Korea)

Author keywords

Aged; Glucose Intolerance; Insulin; Insulin Resistance; Women

Indexed keywords

INSULIN;

AGED; ARTICLE; BODY WEIGHT; FEMALE; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN RESISTANCE; METABOLISM; NON INSULIN DEPENDENT DIABETES MELLITUS; SECRETION;

AGED; AGED, 80 AND OVER; DIABETES MELLITUS, TYPE 2; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; THINNESS;

EID: 0035488205     PISSN: 10118934     EISSN: None     Source Type: Journal    
DOI: 10.3346/jkms.2001.16.5.592     Document Type: Article

References (23)

1. Harris MI, Hadden WC, Knowler WC, Bennett PH. Prevalence of diabetes and impaired glucose tolerance and plasma glucose levels in U.S. population aged 20-74 yr. Diabetes 1987; 36: 523-34.
2. Barrett-Connor E, Ferrara A. Isolated postchallenge hyperglycemia and the risk of fatal cardiovascular disease in older women and men. The Rancho Bernardo Study. Diabetes Care 1998; 21: 1236-9.
3. Meneilly GS, Elliott T, Tessier D, Hards L, Tildesley H. NIDDM in the elderly. Diabetes Care 1996; 19: 1320-5.
4. Lee TH. Prevalence of obesity in Korean non-insulin-dependent diabetic patients. Diabetes Res Clin Pract 1996; 32: 71-80.
5. Min HK. Non-insulin-dependent diabetes mellitus (NIDDM) in Korea. Diabet Med 1996;13:S13-5.
6. Kosaka K, Kuzuya T, Yoshinaga H, Hagura R. A prospective study of health check examinees for the development of non-insulin-dependent diabetes mellitus: relationship of the incidence of diabetes with the initial insulinogenic index and degree of obesity. Diabet Med 1996; 13: S120-6.
7. WHO. Definition, diagnosis and classification of diabetes mellitus and its complications. World Health Organization, Department of Noncommunicable Disease Surveillance, Geneva, 1999.
8. Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985; 28: 412-9.
9. Katz A, Nambi SS, Mather K, Baron AD, Follmann DA, Sullivan G, Quon MJ. Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000; 85: 2402-10.
10. Chen M, Halter JB, Porte D Jr. The role of dietary carbohydrate in the decreased glucose tolerance of the elderly. J Am Geriatr Soc 1987; 35: 417-24.
11. Harris MI. Undiagnosed NIDDM. Clinical and public health issues. Diabetes Care 1993; 16: 642-52.
12. Fink RI, Kolterman OG, Griffin J, Olefsky JM. Mechanisms of insulin resistance in aging. J Clin Invest 1983; 71: 1523-35.
13. Rowe JW, Minaker KL, Pallotta JA, Flier JS. Characterization of the insulin resistance of aging. J Clin Invest 1983; 71: 1581-7.
14. Garcia GV, Freeman RV, Supiano MA, Smith MJ, Galecki AT, Halter JB. Glucose metabolism in older adults: a study including subjects more than 80 yr of age. J Am Geriatr Soc 1997; 45: 813-7.
15. Ahren B, Pacini G. Impaired adaptation of first-phase insulin secretion in postmenopausal women with glucose intolerance. Am J Physiol 1997; 273: E701-7.
16. Duckworth WC, Kitabchi AE. The effect of age on plasma proinsulin-like material after oral glucose. J Lab Clin Med 1976; 88: 359-67.
17. Shaw JE, Hodge AM, de Courten M, Chitson P, Zimmet PZ. Isolated post-challenge hyperglycaemia confirmed as a risk factor for mortality. Diabetologia 1999; 42: 1050-4.
18. DeFronzo RA, Tobin JD, Andres R. Glucose clamp technique: a method for quantifying insulin secretion and resistance. Am J Physiol 1979; 237: E214-23.
19. American Diabetes Association. Consensus development conference on insulin resistance. Diabetes Care 1998; 21: 310-4.
20. Emoto M, Nishizawa Y, Maekawa K, Hiura Y, Kanda H, Kawagishi T, Shoji T, Okuno Y, Morii H. Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Diabetes Care 1999; 22: 818-22.
21. Bonora E, Targher G, Alberiche M, Bonadonna RC, Saggiani F, Zenere MB, Monauni T, Muggeo M. Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: studies in subjects with various degrees of glucose tolerance and insulin sensitivity. Diabetes Care 2000; 23: 57-63.
22. Pigon J, Giacca A, Ostenson CG, Lam L, Vranic M, Efendic S. Normal hepatic insulin sensitivity in lean, mild non-insulin-dependent diabetic patients. J Clin Endocrinol Metab 1996; 81: 3702-8.
23. Meneilly GS, Elliott T. Assessment of insulin sensitivity in older adults using the hyperglycemic clamp technique. J Am Geriatr Soc 1998; 46: 88-91.