Intravenous methadone in the management of chronic cancer pain: Safe and effective starting doses when substituting methadone for fentanyl

Cancer

Volumn 92, Issue 7, 2001, Pages 1919-1925

  Santiago Palma, Juan ^a   Khojainova, Natalia ^a   Kornick, Craig ^a   Fischberg, Daniel J ^b   Primavera, Louis H ^c   Payne, Richard ^a   Manfredi, Paolo ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^c ADELPHI UNIVERSITY   (United States)

Author keywords

Cancer pain; Fentanyl; Methadone; Opioid rotation; Patient controlled analgesia (PCA)

Indexed keywords

FENTANYL; METHADONE; OPIATE;

ADULT; AGED; ARTICLE; CANCER PAIN; CHRONIC PAIN; CLINICAL ARTICLE; CONFUSION; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG WITHDRAWAL; FEMALE; HUMAN; MALE; METHADONE TREATMENT; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEDATION;

ADULT; AGED; ANALGESIA, PATIENT-CONTROLLED; ANALGESICS, OPIOID; DRUG ADMINISTRATION SCHEDULE; FEMALE; FENTANYL; HUMANS; INFUSIONS, INTRAVENOUS; MALE; METHADONE; MIDDLE AGED; NEOPLASMS; PAIN, INTRACTABLE; PALLIATIVE CARE; PROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 0035476291     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/1097-0142(20011001)92:7<1919::AID-CNCR1710>3.0.CO;2-G     Document Type: Article

References (19)

1. Opioid rotation in patients with cancer pain
2. Opioid rotation for toxicity reduction in terminal cancer patients
3. Rapid switching from morphine to methadone in cancer patients with poor response to morphine
4. Opioid rotation for cancer pain
5. Role of methadone in the management of pain in cancer patients
6. Clinical efficacy of methadone in patients refractory to other mu opioid receptor analgesics for the management of terminal cancer pain
7. Individual variability in the response to different opioids: Report of five cases
8. Intravenous methadone for cancer pain unrelieved by morphine and hydromorphone: Clinical observations
9. Methadone in pain uncontrolled by morphine
10. Methadone in the management of cancer pain: A review
11. High dose morphine and methadone in cancer patients. Clinical pharmacokinetic consideration of oral treatment
12. Opioid analgesics and anatagonists
13. Switching from morphine to oral methadone in treating cancer pain: What is the equianalgesic dose ratio?
14. Intravenous high-dose methadone administered by patient controlled analgesia and continuous infusion for the treatment of cancer pain refractory to high-dose morphine
15. Methadone in cancer pain management: Individualize dose and titrate to effect
16. A comparative study of the efficacy and pharmacokinetics of oral methadone and morphine in the treatment of severe pain in patients with cancer
17. When is cancer pain mild, moderate or severe? Grading pain severity by its interference with function
18. Dose ratio between morphine and methadone in patients with cancer pain