Effects of Low Dose Radiation on Signal Transduction of Neurons in Mouse Hypothalamus

Biomedical and Environmental Sciences

Volumn 14, Issue 3, 2001, Pages 248-255

  Wan, Hong ^a,b   Gong, Shou Liang ^a   Liu, Shu Zheng ^a  

^a JILIN UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP; CYCLIC GMP; MESSENGER RNA; PROOPIOMELANOCORTIN;

ANIMAL; ARTICLE; BIOSYNTHESIS; DOWN REGULATION; GENE EXPRESSION REGULATION; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MOUSE; NERVE CELL; ONCOGENE; PATHOPHYSIOLOGY; PHYSIOLOGY; RADIATION EXPOSURE; RADIATION INJURY; RADIATION RESPONSE; SIGNAL TRANSDUCTION;

ANIMAL; CYCLIC AMP; CYCLIC GMP; DOSE-RESPONSE RELATIONSHIP, RADIATION; DOWN-REGULATION; GENE EXPRESSION REGULATION; GENES, FOS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; MICE; NEURONS; PRO-OPIOMELANOCORTIN; RADIATION INJURIES; RNA, MESSENGER; SIGNAL TRANSDUCTION; SUPPORT, NON-U.S. GOV'T;

EID: 0035460673     PISSN: 08953988     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Liu, S. Z. (1995). Current status of research on radiation hormesis in the immune system after low level radiation. J. Radiat. Res. Radiat. Proces. 13, 129-139.
2. Liu, W. H., Gong, S. L., and Liu, S. Z. (1995). Immunological effect of low dose radiation and its mechanism. J. N. Bethune Univ. Med. Sci. 21, 223-226.
3. Liu, S. Z., Van, H., Chen, S. L., and Su, X. (1996). Molecular changes related to the stimulatory effect of low dose radiation on immunity. J. N. Bethune Univ. Med. Sci. 22, 559-566.
4. Gong, S. L., Liu, S. C., Liu, J. X., Zhang, Y. C., and Liu, S. Z. (1998). Adaptive response of thymocyte apoptosis induced by X-irradiation with 75 mGy. J. N. Bethune Univ. Med. Sci. 24, 111-114.
5. Ju, G. Z., Su, X., Song, C. H., and Liu, S. Z. (1999). Immunological adaptive response induced by low dose X-rays. J. N. Bethune Univ. Med. Sci. 25, 559-563.
6. Liu, S. Z., Cai, L., and Sun, S. Q. (1992). Induction of a cytogenetic adaptive response by exposure of rabbits to very low dose rate γ-radiation. Int. J. Radiat. Biol. 62, 187-190.
7. Liu, S. Z. (1998). Biological defense and adaptation induced by low dose radiation. Hum. Ecol. Risk Assess. 4, 1217-1254.
8. b). Signal transduction in lymphocytes after low dose radiation. Int. J. Occup. Med. Toxicol. 3, 107-117.
9. Makinodan, T. and James, J. (1990). T cell potentiation by low dose ionizing radiation: possible mechanisms. Health Physics 59, 29-34.
10. Liu, W. H. and Liu, S. Z. (1992). The effect of low dose X-irradiation on the proliferative response of splenocytes to mitogens. Radiat. Prot. 12, 281-284 (in Chinese).
11. Liu, S. Z., Zhao, Y., Han, Z. B., Gong, S. L., Zhang, M., and Liu, W. H. (1994a). Role of changes in functional status of hypothalamic-pituitary-adrenocortical axis in immunoenhancement after low dose radiation. Chin. J. Radiol. Med. Prot. 14, 11-14 (in Chinese).
12. Gong, S. L., Zhao, Y., and Liu, S. Z. (1996). Role of changes of functional status of hypothalamo-pituitary-gonadal axis in immunoenhancement following low dose radiation. Chin. J. Pathophys. 12, 231-234 (in Chinese).
13. Qiu, Y. H. and Wang, J. H. (1991). Neurotransmitters and neuropeptides on immune functions. Prog. Phys. Sci. 22, 21-24 (in Chinese).
14. Elizabeth, B. (1990). Expression of c-fos-like protein as a marker for neuronal activity following noxious stimulation in the rat. J. Comp. Neurol. 296, 517-530.
15. Morgan, J. I., Cohen, D. R., and Hempstead, J. L. (1987). Mapping patterns of c-fos expression in the central nervous system after seizure. Science 237, 192-195.
16. Sagar, S. M., Sharp, F. R., and Curran, T. Expression of c-fos protein in brain: Metable mapping at the cellular level. Science 240, 1328-1330.
17. Ji, R. R., Zhang, Q., Zhang, M., and Han, J. S. (1993). Induction of Fos-like protein in central nervous system following electroacupuncture stimulation. Chin. Sci. Bull. 38, 370-372 (in Chinese).
18. Wan, H., Gong, S. L., and Liu, S. Z. (1996). Expression of c-fos protooncogene in mouse brain following low dose irradiation. Chin. J. Radiol. Med. Prot. 16, 15-17 (in Chinese).
19. Wan, H. and Liu, S. Z. (1988). Effect of low dose radiation on POMC transcription level in mouse hypothalamus and immune organs. Chin. J. Radiol. Med. Prot. 18, 145-147 (in Chinese).
20. Fang, F. and Liu, J. S. (1998). NO-cAMP signal pathway and regulation. In Cellular Signal and Regulation. (Ed. Liu, J. S., 1st ed.), pp. 207-227. Beijing: Combining Press of Beijing Medical University and Peking Union Medical College (in Chinese).
21. Berkowitz, L. A., Riabowol, K. T., and Cilman, M. Z. (1989). Multiple sequence elements of a single function class are required for cyclic AMP responsiveness of the mouse c-fos promoter. Mol. Cell. Biol. 9, 4292-4296.
22. Chowen-breed, U., Fraser, H. M., Vician, L., and Damassa, U. A. (1989). Testosterone regulation of POMC massager ribonucleic acid in the arcuate nucleus of the male rat. Endocrinology 124, 1697-1702.
23. Sukhov, R. R., Walker, L. C., Rance, N. E., and Pricf, D. L. (1995). Opioid precursor gene expression in the human hypothalamus. J. Comp. Neurol. 353, 604-622.
24. Usui, T., Nakai, Y., and Tsukada, T. (1989). Cyclic AMP-responsive region of the human proopiomelanocortin gene. Mol. Cell. Endocr. 62, 141-146.